Ann Dermatol.  1990 Jul;2(2):132-135. 10.5021/ad.1990.2.2.132.

A Case of Hunter's Syndrome

• Suhr GB
• Lee JH
• Park JK
• Song KY

• KMID: 2362044
• DOI: http://doi.org/10.5021/ad.1990.2.2.132

Abstract

We report a case of Hunter's syndrome in an 8-year-old boy, who presented with ivory-white colored papules and ridges on the left chest area, which were regarded as pathognomonic cutaneous markers for Hunter's syndrome. He also showed growth retardation, dear corneas, hepatosplenomegaly and fair intellect. The histopathological findings of papular lesions revealed loosely arranged collagen fibers with massive mutinous material which stained positively with alcian blue at both pH 2.0 and 0.5. On quantitation of glycosaminoglycans by hexuronic add assay in 24-hour urine, excessive excretion of creatinine was noted. To the best of our knowledge, this is the first case in Korea.

Keyword

Hunter's syndrome

MeSH Terms

Alcian Blue
Child
Collagen
Cornea
Creatinine
Glycosaminoglycans
Humans
Hydrogen-Ion Concentration
Korea
Male
Mucopolysaccharidosis II*
Thorax
Alcian Blue
Collagen
Creatinine
Glycosaminoglycans