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Matrix Production in Chondrocytes Transfected with Sex Determining Region Y-Box 9 and Telomerase Reverse Transcriptase Genes: An In Vitro Evaluation from Monolayer Culture to Three-Dimensional Culture

Noorhidayah MN, Zulkifly A, Khalid KA, Zainol I, Zamli Z, Sha'ban M

BACKGROUND: This study aimed to observe the cartilaginous matrix production in SRY (sex determining region Y)-box 9 (SOX9)- and/or telomerase reverse transcriptase (TERT)-transfected chondrocytes from monolayer to three-dimensional (3D) culture. METHODS:...
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Induction of Chondrogenic Differentiation in Human Mesenchymal Stem Cells Cultured on Human Demineralized Bone Matrix Scaffold under Hydrostatic Pressure

Shahmoradi SR, Kabir Salmani M, Soleimanpour HR, Tavakoli A, Hosaini K, Haghighipour N, Bonakdar S

BACKGROUND: Articular cartilage damage is still a troublesome problem. Hence, several researches have been performed for cartilage repair. The aim of this study was to evaluate the chondrogenicity of demineralized...
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Tissue Regeneration of Human Mesenchymal Stem Cells on Porous Gelatin Micro-Carriers by Long-Term Dynamic In Vitro Culture

Nguyen L, Bang S, Noh I

BACKGROUND: Tissue engineering is a multidisciplinary field which attracted much attention in recent years. One of the most important issue in tissue engineering is how to obtain high cell numbers...
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Study of the cartilage matrix production-promoting effect of chicken leg extract and identification of the active ingredient

Yamada H, Nakamura U, Nakamura T, Uchida Y, Yamatsu A, Kim M

BACKGROUND/OBJECTIVES: Osteoarthritis (OA) is a major public health issue in Japan and other countries, and foods that prevent or treat OA are in strong demand. Proteins and peptides in chicken...
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Epithelial ovarian tumors in a premenarchal girl: a rare case report

Ojha P, Nigam JS, Deshpande , Gargade CB

Ovarian tumors are relatively uncommon in paediatric age group and mostly occur in the period after menarche and are extremely rare prior to menarche. However, in children and adolescent, the...
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Novel Approach Toward the Generation of Tissue Engineered Heart Valve by Using Combination of Antioxidant and Detergent: A Potential Therapy in Cardiovascular Tissue Engineering

Tardalkar , Desai S, Adnaik A, Bohara R, Joshi M

To develop decellularized heart valve scaffold from porcine for heart valve regeneration. Porcine heart valves were decellularized with unique optimized approach by using 1% sodium dodecyl sulfate solution and 5%...
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Aloe-Emodin Induces Chondrogenic Differentiation of ATDC5 Cells via MAP Kinases and BMP-2 Signaling Pathways

Yang M, Li L, Heo SM, Soh Y

Endochondral bone formation is the process by which mesenchymal cells condense into chondrocytes, which are ultimately responsible for new bone formation. The processes of chondrogenic differentiation and hypertrophy are critical...
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A Case of Self-healing Juvenile Cutaneous Mucinosis

Moon SH, Jeong WS, Lee TG, Kwon TG, Lee SK

  • KMID: 2368896
  • Korean J Dermatol.
  • 2016 Dec;54(10):814-818.
Self-healing juvenile cutaneous mucinosis (SHJCM) is a rare disorder of unknown origin that affects healthy children. It is characterized by multiplication of transient papules and nodules on the head and...
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Derivation and Differentiation of Bone Marrow Mesenchymal Stem Cells from Osteoarthritis Patients

Gari M, Alsehli H, Gari A, Abbas M, Alkaff M, Abuzinadah M, Al-Sayes F, Gari M, Dallol A, Abuzenadah AM, Gauthaman

Osteoarthritis (OA) of the knee is a degenerative joint disease caused by the progressive reduction of the articular cartilage surface that leads to reduced joint function. Cartilage degeneration occurs through...
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Effect of dual-type oligosaccharides on constipation in loperamide-treated rats

Han SH, Hong KB, Kim EY, Ahn SH, Suh HJ

BACKGROUND/OBJECTIVES: Constipation is a condition that can result from intestinal deformation. Because humans have an upright posture, the effects of gravity can cause this shape deformation. Oligosaccharides are common prebiotics...
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A Clinicopathologic Study of Clear Cell Actinic Keratosis

Kim BK, Ahn SK

  • KMID: 2245843
  • Korean J Dermatol.
  • 2015 Sep;53(8):594-603.
BACKGROUND: Clear cells are defined as cells that contain abundant, clear, lightly eosinophilic cytoplasm. On rare occasions, clear cell changes have been observed in actinic keratosis (AK). OBJECTIVE: We aimed to...
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Periadnexal Mucin as an Additional Histopathologic Feature of Chronic Eczematous Dermatitis

Lee NR, Kim JH, Park HY, Yoon NY, Ahn SK

BACKGROUND: Cutaneous mucinoses are a heterogeneous group of disorders characterized by an abnormal amount of mucin in the skin. However, the pathomechanism of an excessive mucin deposition in the skin...
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Mucinous precursor lesions of mucinous carcinoma in breast: Incidence and histopathologic features

Jung MJ, Kim YO

OBJECTIVES: Columnar cell lesion (CCL), atypical ductal hyperplasia (ADH) and ductal carcinoma in situ (DCIS) may be premalignant lesion of mammary invasive carcinoma. A few recent investigators reported that the...
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Plexiform Angiomyxoid Myofibroblastic Tumor of the Stomach: Report of a Case and Review of the Literature

Baek SH, Yoon JH, Kim JY

We report a case of a plexiform angiomyxoid myofibroblastic tumor of the stomach that developed in a 38-year-old woman who underwent gastrofiberscopy and multi-detector computed tomography scans due to dyspepsia...
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Histologic Changes of Vocal Fold Aging in a Rat Model

Lim DW, Choi JS, Lim JY, Kim YM

BACKGROUND AND OBJECTIVES: Aging causes atrophy in mucosa of vocal folds, resulting in various deleterious changes in phonation. Eventually, these changes impair an elderly individual's ability to communicate with others...
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A Case of Clear Cell Basal Cell Carcinoma

Kwon SY, Park SH, Kim UK, Park K, Park SD

  • KMID: 2088726
  • Korean J Dermatol.
  • 2013 Jul;51(7):548-551.
Clear cell basal cell carcinoma is a rare histological variant of basal cell carcinoma, which is characterized by a variable component of clear cells. We report a case of clear...
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Histopathological Findings of Hemorrhagic Ganglion Cyst Causing Acute Radicular Pain: A Case Report

Park JH, Im SB, Kim HK, Hwang SC, Shin DS, Shin WH, Kim BT

Although juxtafacet cysts of the lumbar spine are being reported with increasing frequency, hemorrhage from a ganglion cyst is rare, and the pathophysiologic mechanism of the hemorrhage from the cyst...
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Change of Glycosaminoglycan Distribution and Collagen Fibers Arrangement on Temporomandibular Joint Following Anterior Disc Displacement of the Rabbits

Kim UK, Chung IK, Kim KC

  • KMID: 1969972
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2012 May;34(3):173-179.
PURPOSE: This study was to determine the effects of surgical induction of anterior disc displacement (ADD) on the distribution of glycosaminoglycan (GAG) and collagen fiber arrangement in the rabbit temporomandibular...
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The Role of CDX2 in Intestinal Metaplasia Evaluated Using Immunohistochemistry

Lee BH, Kim N, Lee HS, Kang JM, Park HK, Jo HJ, Shin CM, Lee SH, Park YS, Hwang JH, Kim JW, Jeong SH, Lee DH, Jung HC, Song IS

  • KMID: 2167366
  • Gut Liver.
  • 2012 Jan;6(1):71-77.
BACKGROUND/AIMS: Intestinal metaplasia (IM) has been regarded as a premalignant condition. This study evaluated the role of the transforming factor CDX2 according to the severity and type of IM. METHODS: This...
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A Case of Herpetiform Appearance of Digital Mucous Cysts

Hur J, Kim YS, Yeo KY, Kim JS, Yu HJ

A digital mucous cyst (DMC) is clinically characterized by a round to oval, translucent, smooth nodule localized to the dorsal aspect of the distal digits near the distal interphalangeal joint....
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