J Audiol Otol.  2016 Dec;20(3):139-145. 10.7874/jao.2016.20.3.139.

Fibrinogen-Based Collagen Fleece Graft Myringoplasty for Traumatic Tympanic Membrane Perforation

• Choi SH
• Song HY
• Song CI

• KMID: 2361686
• DOI: http://doi.org/10.7874/jao.2016.20.3.139

Abstract

BACKGROUND AND OBJECTIVES
The aim of this study was to investigate how fibrinogen-based collagen fleece (Tachocomb®) graft myringoplasty (FCGM), performed under microscopic guidance, improves both hearing and tympanic membrane tissue repair in patients with traumatic tympanic membrane perforation (TMP).
SUBJECTS AND METHODS
Between August 2009 and March 2015, a total of 52 patients with traumatic TMP visited the department of otorhinolaryngology at a secondary medical center. Twenty-nine of these underwent FCGM under microscopic guidance in our outpatient clinic. For each patient, we recorded the location and size of the perforation, the time elapsed from the onset of TMP until the myringoplasty, and the hearing level both before and after myringoplasty.
RESULTS
The TMP closed completely in all cases (29 of 29 patients). After myringoplasty, the postoperative air-bone gap (ABG) differed significantly from the preoperative ABG. Three of the 29 patients (10.3%) experienced complications. Specifically, 2 presented with otorrhea after FCGM, but conservative management led to improvement without recurrence of perforation. One patient showed delayed facial palsy 1 week after the procedure. The condition of this patient also improved and the palsy was not permanent.
CONCLUSIONS
FCGM may be an effective treatment option in case of traumatic TMP. The procedure requires no hospitalization, and can be used to avoid traditional tympanoplasty.

Keyword

Tympanic membrane perforation; Fibrinogen-based collagen fleece; Myringoplasty; Conductive hearing loss; Patch

MeSH Terms

Ambulatory Care Facilities
Collagen*
Facial Paralysis
Hearing
Hearing Loss, Conductive
Hospitalization
Humans
Myringoplasty*
Otolaryngology
Paralysis
Recurrence
Thymidine Monophosphate
Transplants*
Tympanic Membrane Perforation*
Tympanic Membrane*
Tympanoplasty
Collagen
Thymidine Monophosphate