The Effect of the Amniotic Membrane on Treatment of Tympanic Membrane Perforation

Mun, Seog Kyun; Cho, Hang Sun; Lee, Gyu Ho; Lee, Kwang Ho; Do, Youn Kyoung; Hong, Young Ho

Abstract

BACKGROUND AND OBJECTIVES: Tympanic membrane perforations are usually caused by trauma, infection, surgical procedures such as tympanoplasty or myringoplasty. Because perforations interfere with the transmission and perception of sound, whatever the cause of the perforation, repair of the membrane is desirable. The purpose of this study is to investigate the clinical application and usefulness of allograft amniotic membrane, instead of autograft materials, in the management of tympanic membrane perforation.
SUBJECTS AND METHOD
A retrospective study was performed on 14 patients who underwent myringoplasty with allograft amniotic membrane for tympanic membrane perforation from October 2006 to September 2007. Information was collected on sex, age, the cause of perforation, the perforation size, postoperative hearing result, the success rate.
RESULTS
Of 14 patients, 13 patients were successfully treated by myringoplasty with allograft amniotic membrane and one patient failed due to infection. So the overall success rate was 93%. The mean air-bone gap was improved from 13.3 dB to 7.1 dB.
CONCLUSION
The myringoplasty with allograft amniotic membrane is a successful procedure for the healing of tympanic membrane perforations.