Korean J Urol Oncol.  2016 Aug;14(2):93-96. 10.22465/kjuo.2016.14.2.93.

Female Prostate? - Clear Cell Adenocarcinoma of Female Urethra

• You JH
• Kim MK

• KMID: 2361570
• DOI: http://doi.org/10.22465/kjuo.2016.14.2.93

Abstract

Clear cell adenocarcinoma of the female urethra is extremely rare. Because the primary urethral carcinomas are rare, standard diagnostic algorism and management has not been established yet. We report a case of clear cell adenocarcinoma of the proximal urethra in a 76-year-old female. She was presented with voiding difficulty for several years after pubovaginal sling operation due to stress urinary incontinence twelve years ago. Before this period, she had managed with medication for detrusor hypocontractility. Recently she complained bloody vaginal discharge, and her vaginal examination revealed palpable mass on the anterior vaginal wall. Pelvic MRI showed a 5×4.5cm sized tumor surrounding the proximal urethra which was mimicking prostate with no lymphadenopathy. Biopsy of the mass confirmed it to be clear cell adenocarcinoma. She underwent anterior pelvic exenteration and ileal conduit with bilateral pelvic lymph node dissection. The patient received adjuvant radiotherapy and chemotherapy as treatment. We should carefully evaluate patients with voiding symptom after anti-incontinence surgery and multimodal treatment should be applied for locally advanced urethral carcinoma.

Keyword

Urethral carcinoma; Clear cell adenocarcinoma; Pubovaginal sling operation

MeSH Terms

Adenocarcinoma, Clear Cell*
Aged
Biopsy
Combined Modality Therapy
Drug Therapy
Female*
Gynecological Examination
Humans
Lymph Node Excision
Lymphatic Diseases
Magnetic Resonance Imaging
Pelvic Exenteration
Prostate*
Radiotherapy, Adjuvant
Urethra*
Urinary Diversion
Urinary Incontinence
Vaginal Discharge