J Korean Radiol Soc.  1987 Aug;23(4):581-589. 10.3348/jkrs.1987.23.4.581.

The effects of prostaglandin E1 on peripheral arteriography

• Lee SC
• Kwon YH
• Joo JH
• Sohn HK
• Seo HS
• Hahm CK
• Kim SY

• KMID: 2359425
• DOI: http://doi.org/10.3348/jkrs.1987.23.4.581

Abstract

The effectiveness and side effects intraarterial use of prostaglandin E1(PGE1) as a vasodilator were evaluatedin 40 peripheral arteriographies which were performed on 20 patients at Hanyang University Hospital from Dec. 1985to Mar. 1987. Both control and PGE1-used arteriographies were performed on each patient. In PGE1, study, 20 microg of prostaglandin E1 was slowly injected for 30 seconds intraarterially 30 seconds before injection of contrastmedia. The peripheral arteriographices using intraarterial PGE1 were more effective in diagnostic arteriography without any significant hemodynamic side effects. The results were as follows: 1. The PGE1-used arteriograms revealed more earlier visualization of optimal phase than control arteriograms in most of the patients, as well asin visualization of venous system. 2. There were greater incidence of peripheral visualization of arterial branches and improved opacification of arterial system in PGE1-used arteriograms than in control arteriograms. 3.In PGE1 study, the total amount and injection speed of contrast media should be increased to obtaine better arteriogram. 4. There was no significant hemodynamic side effects after intraarterial use of prostaglandin E1.

MeSH Terms

Alprostadil*
Angiography*
Contrast Media
Hemodynamics
Humans
Incidence
Alprostadil
Contrast Media