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Clinical efficacy of angiotensin receptor-neprilysin inhibitor in de novo heart failure with reduced ejection fraction

Park SY, Kong MG, Moon I, Park HW, Choi HO, Seo HS, Cho YH, Lee NH, Lee KY, Jang HJ, Kim JS, Choi IJ, Suh J

Background/Aims: We aimed to analyze the efficacy of angiotensin receptor-neprilysin inhibitor (ARNI) by the disease course of heart failure (HF). Methods: We evaluated 227 patients with HF in a multi-center retrospective...
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Temporal Trend of the Incidence and Characteristics of Renal Infarction: Korean Nationwide Population Study

Kim DE, Moon I, Park S, Park M, Park S, Kwon SS, Kong MG, Park HW, Choi HO, Seo HS, Cho YH, Lee NH, Suh J

Background: Large-scale studies about epidemiologic characteristics of renal infarction (RI) are few. In this study, we aimed to analyze the incidence and prevalence of RI with comorbidities in the South...
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In vitro and in vivo evaluation of the genotoxicity of titanium dioxide, GST

Kim JS, Jeong MH, Seo HS, Park MK, Park HJ, Nah SS

Titanium dioxide (TiO2) was used in various applications in a wide range of products including food, cosmetics and photocatalyst. General toxicity studies of titanium dioxide, GST (Green Sludge Titanium) have...
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Psychometric Properties of the Korean Version of 12-Item Obsessive-Compulsive Inventory in Accordance With Obsessive-Compulsive Symptom Dimensions in Individuals With Obsessive-Compulsive Disorder

Seo HS, Choi M, Lee SJ

Objective : The 18-item Obsessive-Compulsive Inventory-Revised (OCI-R) is widely employed to assess symptoms of obsessive-compulsive disorder (OCD). However, this instrument’s factor structure does not align with contemporary dimensional models of...
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Left Atrial Velocity Vector Imaging Can Assess Early Diastolic Dysfunction in Left Ventricular Hypertrophy and Hypertrophic Cardiomyopathy

Yoon SJ, Park S, Choi EY, Seo HS, Shim CY, Ahn CM, Kim SA, Ha JW

BACKGROUND: The function of left atrium (LA) is difficult to assess because of its ventricledependent, dynamic movement. The aim of this study was to assess LA function using velocity vector...
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Twenty-eight-day oral dose toxicity evaluation of SUNACTIVE Fe-P80 in rats

Lim JH, Park MK, Seo HS, Kim SH, Kim WI, Shin IS, Kim JC

Iron deficiency is known to be a common nutritional disorder in many countries, especially among children, women of childbearing age and pregnant women. SUNACTIVE Fe-P80 is a new type of...
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Surgical Procedures Requiring Hospitalization and Perioperative Management for Patients with Hereditary Bleeding Disorders

Seo HS, Ahn WK, Hahn SM, Han JW, Lyu CJ

Background: Hemophilia requires a lifetime care for bleeding control and complications. Although patients diagnosed with hemophilia receive factor replacement, they also experience a variety of medical problems as they age....
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Screening of Plant-Derived Natural Extracts to Identify a Candidate Extract Capable of Enhancing Lipid Synthesis in Keratinocytes

Lee SH, Seo HS, Seo SJ, Kim CD, Hong SP

Background: Reduced lipid content in the stratum corneum is a major cause of skin-barrier dysfunction in various pathological conditions. Promoting lipid production is a potential strategy to improve skin-barrier function....
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The First Systematic Gastroscopy Training Program for Surgeons in Korea

Seo HS, Kim SJ, Jeon CH, Song KY, Lee HH

Background: Endoscopic evaluation of the stomach is essential for preoperative planning and post-surgical surveillance for various diseases of the stomach, including malignancy. The gastroscopy education program for surgeons is currently in...
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Reproductive and developmental toxicity screening test of new TiO2 GST in Sprague-Dawley rats

Baek HS, Park MK, Kim HM, Im JM, Seo HS, Park HJ, Nah SS

TiO2 nanoparticles are widely used in paints, plastics, cosmetics, printing ink, rubber, food products, pharmaceuticals and other products (photocatalyst, etc.). However, there is little toxicological information during reproduction and developmental...
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Comparison of Clinical Outcomes of Long Stent Implantation with First- and Second-Generation Drug-Eluting Stents Following Rotational Atherectomy

Kim D, Park S, Moon I, Kong MG, Park HW, Choi HO, Seo HS, Suh J, Lee NH, Cho YH

Objective: Rotational atherectomy (RA) and newly developed second-generation drug-eluting stent (DES) support the strategy of longer stent deployment in comparison to short stent implantations in the past. However, studies analyzing...
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Fimasartan Ameliorates Deteriorations in Glucose Metabolism in a High Glucose State by Regulating Skeletal Muscle and Liver Cells

Jang YN, Lee YJ, Han YM, Kim HM, Seo HS, Jeong JH, Park SY, Jung TW

Purpose: Since diabetes and hypertension frequently occur together, it is thought that these conditions may have a common pathogenesis. This study was designed to evaluate the anti-diabetic function of the...
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Repeated-dose 90-day oral toxicity study of GST in Sprague-Dawley rats

Kim SH, Park MK, Seol JK, Im JM, Seo HS, Park HJ, Nah SS

TiO2 have been studied on inhalation and skin exposure due to the properties of the materials’ use (cosmetics, paints and other products) and the additional safety information on other intake...
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Repeated-dose 28-day dermal toxicity study of TiO2 catalyst (GST) in Sprague-Dawley rats

Kim JH, Park Mk, Im JM, Seo HS, Park HJ, Nah SS

TiO2 have been studied on inhalation and skin exposure due to the properties of the materials’ use (cosmetics, paints and other products) and the additional safety information on other intake...
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Chronological trends in patients undergoing cholecystectomy in Korea: a nationwide health insurance claims study

Jeon CH, Hong J, Jung J, Moon JY, Seo HS

Purpose: The incidence of gallstone disease and cholecystectomy is increasing worldwide. The aim of this study was to determine trends in the incidence of cholecystectomy in Korea. Methods: The National Health...
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Stimulation of Alpha-1-Adrenergic Receptor Ameliorates Obesity-Induced Cataracts by Activating Glycolysis and Inhibiting Cataract-Inducing Factors

Lee YJ, Jang YN, Kim HM, Han YM, Seo HS, Eom Y, Song Js, Jeong JH, Jung TW

Background: Obesity, the prevalence of which is increasing due to the lack of exercise and increased consumption of Westernized diets, induces various complications, including ophthalmic diseases. For example, obesity is...
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Short Review on Advances in Hydrogel-Based Drug Delivery Strategies for Cancer Immunotherapy

Seo HS, James Wang CP, Park W, Park CG

Cancer immunotherapy has become the new paradigm of cancer treatment. The introduction and discovery of various therapeutic agents have also accelerated the application of immunotherapy in clinical trials. However, despite...
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Relationship Between Appendectomy Incidence and Computed Tomography Scans Based on Korean Nationwide Data, 2003–2017

Park KB, Hong J, Moon JY, Jung J, Seo HS

Background: Advances in medicine and changes in the medical environment can affect the diagnosis and treatment of diseases. The main purpose of the present study was to investigate whether the...
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Factors Influencing Oncology Nurses’ Pain Management of Cancer Patients

Seo HS, Park EY, Park SJ, Han BR, Jang MJ

Purpose: The purpose of this study is to investigate the factors influencing oncology unit nurses’ pain management of cancer patients. Methods: This study was a designed descriptive correlation study. The...
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Peer Review of Teleradiology at a Teleradiology Clinic: Comparison of Unacceptable Diagnosis and Clinically Significant Discrepancy between Radiology Sections and Imaging Modalities

Seo HS, Park JS, Oh YW, Sung D, Lee AL

Purpose The purpose of this study was to evaluate the rates of unacceptable diagnosis and clinically significant diagnostic discrepancy in radiology sections and imaging modalities through a peer review of...
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