J Korean Radiol Soc.  1989 Jun;25(3):485-492. 10.3348/jkrs.1989.25.3.485.

Radiological evaluation of neuroblastoma

• Cha SS
• Kwun DY
• Kim JD
• Eun TK
• Chung DH

• KMID: 2359115
• DOI: http://doi.org/10.3348/jkrs.1989.25.3.485

Abstract

Neuroblasatoma is one of common malignancy in children, and originates from the primitive sympathetic neuroblasts of the embryonic neural crest. Because of the patient have disseminated disease at the time of diagnosis, the prognosis will not be good. Nowadays, we will have more accurate information for diagnosing and staging by applications of modern imaging modalities. The authors analyzed radiological findings of 21 case as of pathologically proven neuroblastoma at Inje University Pusan Paik Hospital. The results were as follows; 1. The mean age was 4 year-old, and male to female ratio was 11:10. 2. The most common clinical finding was palpable abdominal mass(10 cases), and the most common originating site was abdomen(17 cases). The diagnosis could be donein 9 cases by clinical impression. 3. Neuroblalstoma was in 19 cases and ganglioneuroblastoma was in 2 cases pathologically stage I was in 1 cases, and the others(20 cases) were more than stage III. 4. Among 19 cases, plainfilm and IVP showed renal abnormality in 16 cases, calcification in 6 cases and bone metastases in 10 cases. 5. Among 13 cases, ultrasonography showed irregularly marginated, heterogenous mass in 12 cases, calcification in 8cases, renal abnormality in 9 cases, and lymph node metastases in 10 cases. 6. Among 12 cases, CT finding showed irregular margined soft tissue mass in 11 cases, calcification in 9 cases, renal abnormality in 9 cases, lymphnode metastases in 11 cases and bone metastases in 4 cases. 7. Among 15 cases, bone scintigraphy showed bone metastases in 11 cases, renal abnormality in 9 cases and primary site uptake in 9 cases.

MeSH Terms

Busan
Child
Diagnosis
Female
Ganglioneuroblastoma
Humans
Lymph Nodes
Male
Neoplasm Metastasis
Neural Crest
Neuroblastoma*
Prognosis
Radionuclide Imaging
Ultrasonography