J Korean Radiol Soc.  1989 Dec;25(6):873-876. 10.3348/jkrs.1989.25.6.873.

Hypothalamic hamartoma associated with precocious puberty: case report

• Bae WK
• Kim PN
• Kim IY
• Lee BH
• Lee KS
• Bae HG
• Yun IG

• KMID: 2359018
• DOI: http://doi.org/10.3348/jkrs.1989.25.6.873

Abstract

Hamartoma of the hypothalamic area is a well-recognized cause of central precocious puberty. We report a case of histologically proven hypothalamic hamartoma in a 8-year-old girl with precocious puberty. The CT showed anisodense, nonenhancing mass in suprasellar area, measuring 4.2×3.1cm, which , to our knowledge, seems to be the largest one of the published cases. On MR imaging, the signal intensity of the mass was homogenous and isointense relative to gray matter on T1- and hyperintense on T2-weighted images. The clinical and radiologic findings of the published cases of hypothalamic hamartoma are reviewed.

MeSH Terms

Child
Female
Gray Matter
Hamartoma*
Humans
Magnetic Resonance Imaging
Puberty, Precocious*