J Korean Radiol Soc.  1990 Feb;26(1):1-12. 10.3348/jkrs.1990.26.1.1.

An experimental study on high-field MR imaging of acute and subacute intracerebral hematoma

• Han MH
• Chang KH
• Han MC

• KMID: 2358967
• DOI: http://doi.org/10.3348/jkrs.1990.26.1.1

Abstract

To clarify the findings in acute and subacute intracerebral hematoma on 2.0T MRT, to evaluate the diagnosticvalue of each pulse sequences, and to obtain the valuable informations determinign the age of the lesion, the MRIwas performed sequentially in experimental model of intracerebral hematoma. Sixteen cats were used as enperimentalanimal, and the lesions were made by the injection of arterial blood into the brain parenchyme. The MRI wasperformed by spin echo technique with TR and TE of 500/30 and 3000/30, 80, and by gradient echo technique with 300/12. The relative signal intensities of hematoma and surrounding parenchyme were calculated as compared withcontralateral normal white matter and the findings and differences on the time intervals and imaging techniqueswere analyzed. Most of the intracerebral hematomas were seen as iso of low intensity on T1 and T2 wieghted imagesimmediately after bleeding, and as high intenstiy on T1 weighted image from 4 days to 1 week. The high intensityof surrounding parenchyme on T1 and T2 weighted images were found upto 1 week and diminished after then. The lowsignal intensity of peripheral portion of the lesion connot be explained clearly, however, the bundary effect dueto different susceptibility and the free radicals ain macrophages during acute phase and the hemosiderindeposition in subacute phase are thought as the possible cause of the low intensity.

MeSH Terms

Animals
Brain
Cats
Free Radicals
Hematoma*
Hemorrhage
Macrophages
Magnetic Resonance Imaging*
Models, Theoretical
White Matter
Free Radicals