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MicroRNA-10b Plays a Role in Bone Formation by Suppressing Interleukin-22 in Ankylosing Spondylitis

Park PR, Jo S, Jin SH, Kim TJ

OBJECTIVE: The microRNA (miR)-10b is the T helper (Th) 17 cell specific in patients with ankylosing spondylitis (AS). The interleukin (IL)-22, which is closely related to Th17 cells, has been...
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Experimental modeling of the acute toxicity and cytogenotoxic fate of composite mixtures of chromate, copper and arsenate oxides associated with CCA preservative using Clarias gariepinus (Burchell 1822)

Fagbenro O, Alimba CG, Bakare AA

Concurrent occurrence of chromium (Cr), copper (Cu) and arsenic (As) from chromated copper arsenate (CCA) wood preservative in aquatic ecosystems demands that their joint-actions in eliciting toxic effects be assessed...
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Worsened survival in the head-up tilt position cardiopulmonary resuscitation in a porcine cardiac arrest model

Park YJ, Hong KJ, Shin SD, Kim TY, Ro YS, Song KJ, Ryu HH

OBJECTIVE: Head elevation at an angle of 30° during cardiopulmonary resuscitation (CPR) was hemodynamically beneficial compared to supine position in a previous porcine cardiac arrest experimental study. However, survival benefit...
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Toward a grey box approach for cardiovascular physiome

Hwang M, Leem CH, Shim EB

The physiomic approach is now widely used in the diagnosis of cardiovascular diseases. There are two possible methods for cardiovascular physiome: the traditional mathematical model and the machine learning (ML)...
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Emerging Themes for the Role of Antibodies in Tuberculosis

Tran AC, Kim MY, Reljic R

The best way to debunk a scientific dogma is to throw irrefutable evidence at it. This is especially true if the dogma in question has been nurtured over many decades,...
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Bifidobacterium infantis Induces Protective Colonic PD-L1 and Foxp3 Regulatory T Cells in an Acute Murine Experimental Model of Inflammatory Bowel Disease

Zhou L, Liu D, Xie Y, Yao X, Li Y

BACKGROUND/AIMS: The current study aims to investigate the protective effects of Bifidobacterium infantis on the abnormal immune response to inflammatory bowel disease (IBD) in dextran sodium sulfate (DSS)-induced colitis. METHODS: Eight-week-old...
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Internet of Things Applied in Healthcare Based on Open Hardware with Low-Energy Consumption

Ramirez Lopez LJ, Puerta Aponte G, Rodriguez Garcia A

OBJECTIVES: The Internet of Things (IoT) and its applications are growing simultaneously. These applications need new intelligent devices along heterogeneous networking. Which makes them costly to implement indeed. Platforms and...
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Effective Parameters for Gait Analysis in Experimental Models for Evaluating Peripheral Nerve Injuries in Rats

Matias Júnior I, Medeiros P, de Freita , Vicente-César H, Ferreira Junior JR, Machado HR, Menezes-Reis R

OBJECTIVE: Chronic constriction injury (CCI) of the sciatic nerve is a peripheral nerve injury widely used to induce mononeuropathy. This study used machine learning methods to identify the best gait...
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Preclinical Efficacy of [V⁴Q⁵]dDAVP, a Second Generation Vasopressin Analog, on Metastatic Spread and Tumor-Associated Angiogenesis in Colorectal Cancer

Garona J, Sobol NT, Pifano M, Segatori V, Gomez DE, Ripoll GV, Alonso DF

PURPOSE: Control of metastatic spread of colorectal cancer (CRC) remains as a major therapeutic challenge. [V4 Q5 ]dDAVP is a vasopressin peptide analog with previously reported anticancer activity against carcinoma...
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Circulating Permeability Factors in Idiopathic Nephrotic Syndrome

Ha TS

Nephrotic syndrome (NS) is a common chronic glomerular disease in children characterized by significant proteinuria with resulting hypoalbuminemia, edema, and hyperlipidemia. Renal biopsy findings of diffuse foot processes effacement on...
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A Predictive Model on Patient-Centered Care of Hospital Nurses in Korea

Jeong H, Park M

PURPOSE: Patient-centered care is a widely utilized concept in nursing and health care. However, the key components of patient-centered nursing have not yet been reported. Moreover, previous studies on patient-centered...
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Anti-Migration and Anti-Invasion Effects of Curcumin via Suppression of Fascin Expression in Glioblastoma Cells

Park KS, Yoon SY, Park SH, Hwang JH

BACKGROUND: The natural compound curcumin was known to inhibit migration and invasion of glioblastoma (GBM) cells. Fascin, a kind of actin-binding proteins, is correlated with migration and invasion of GBM...
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Acute toxicity of copper hydroxide and glyphosate mixture in Clarias gariepinus: interaction and prediction using mixture assessment models

Kingsley K

The study aimed to assess the single and joint lethal toxicity, type of interaction and the extent to which simple mathematical model of concentration addition (CA), independent action (IA) and...
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Trend Analysis of Theory-based Research Published in Asian Oncology Nursing

Lee HY, Kim MK, Seo WJ, Lee MJ, Heo YR, Kim S

PURPOSE: This study was conducted to identify and analyze the trends of theory-based research published in Asian Oncology Nursing (AON) from 2011 to 2017. METHODS: We analyzed 22 theory-based studies taken...
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Development and Validation of the Communication Behavior Scale for Nurses Caring for People with Dementia

Lee J, Gang M

PURPOSE: The purpose of this study was to develop and validate the Communication Behavior Scale for nurses caring for people with Dementia (CBS-D). METHODS: Based on communication accommodation theory, the initial...
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Bladder Augmentation Using Lyoplant® : First Experimental Results in Rats

Winde F, Backhaus K, Zeitler JA, Schlegel N, Meyer T

BACKGROUND: Congenital defects of the urinary bladder (micro- or contracted bladder, bladder exstrophy) remain a challenging problem for pediatric surgeons. Even when conservative treatment options are fully exhausted, irreversible renal...
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Protective effect of glucosamine and risedronate (alone or in combination) against osteoarthritic changes in rat experimental model of immobilized knee

Salman A, Shabana AI, El-ghazouly DEs, Maha E

This study is aiming to investigate the protective effect of glucosamine, risedronate (alone or in combination) on articular cartilage in experimental model of immobilized rat knee. Twenty-five adult male albino...
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Effects of Platelet-rich Plasma on Ocular Surface in Patients with Dry Eye Syndrome: Clinico-experimental Analysis

Jung JU, Lee SH, Kim HK

PURPOSE: To evaluate the effect of platelet rich plasma (PRP) on ocular surface damage caused by hyperosmotic conditions using retrospective clinical and experimental analyses. METHODS: Eighty eyes of moderate dry eye...
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Human ex vivo and in vitro disease models to study food allergy

Hung L, Obernolte , Sewald K, Eiwegger T

Food allergy is a growing global public health concern. As treatment strategies are currently limited to allergen avoidance and emergency interventions, there is an increasing demand for appropriate models of...
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A Novel Method to Study the Effects of Cyclosporine on Gingival Overgrowth in Children

Han K, Kim J

Previous studies to elucidate the etiology of cyclosporine(Cs)-induced gingival overgrowth in children have not completely excluded all factors that may cause differences among individuals. This study examined the effect of...
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