Korean J Anesthesiol.  1976 Dec;9(2):203-208.

Serum Testosterone in Man during Halothane Anesthesia and Surgery

• Park SJ
• Chon SU

Abstract

The relationship between the Leydig cell of testis and the tropic hormones of the anterior pituitary gland has been inadequately explored in man because of methodological difficulties. Ether anesthesia has been shown to increase testicular blood level of testosterone in man. Some report has appeared on the effect of anesthesia person sex hormone levels in human serum. As testosterone is one of the most important anabolic hormones, it would therefore serve as an index to hormonal response to stress in man. Testosterone levels were measured by Oyama et al by competitive protein binding method. This study was done to investigate the effect of halothane anesthesia and surgery on human sex hormone by radioimmunoassay method. Serum testosterone levels measured at preanesthetic period, 60 minutes after anesthesia and surgery, and full recovery from anesthesia were 4. 18+/-l. 64 ng/ml, 4. 19+/-1.40 ng/ml and 3. 74+/-1. 65 ng/ml, respectively. No statistical significance was noticed each other. The obtained value of testosterone was the lowest compared with the values reported by other authors.

MeSH Terms

Anesthesia*
Ether
Halothane*
Humans
Methods
Pituitary Gland, Anterior
Protein Binding
Radioimmunoassay
Testis
Testosterone*
Ether
Halothane
Testosterone