Ultrasonography.  2016 Oct;35(4):302-308. 10.14366/usg.16026.

Applications of acoustic radiation force impulse quantification in chronic kidney disease: a review

Affiliations
  • 1Department of Ultrasound, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing, China. bryan_pumch@163.com

Abstract

Acoustic radiation force impulse (ARFI) imaging is an emerging technique with great promise in the field of elastography. Previous studies have validated ARFI quantification as a method of estimating fibrosis in chronic liver disease. Similarly, fibrosis is the principal process underlying the progression of chronic kidney disease, which is the major cause of renal failure. However, the quantification of tissue stiffness using ARFI imaging is more complex in the kidney than in the liver. Moreover, not all previous studies are comparable because they employed different procedures. Therefore, subsequent studies are warranted, both in animal models and in clinical patients, in order to better understand the histopathological mechanisms associated with renal elasticity and to further improve this imaging method by developing a standardized guidelines for its implementation.

Keyword

Renal insufficiency, chronic; Kidney failure, chronic; Elasticity imaging techniques

MeSH Terms

Acoustics*
Elasticity
Elasticity Imaging Techniques
Fibrosis
Humans
Kidney
Kidney Failure, Chronic
Liver
Liver Diseases
Methods
Models, Animal
Renal Insufficiency
Renal Insufficiency, Chronic*
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