J Korean Dent Soc Anesthesiol.  2002 Jun;2(1):27-32. 10.17245/jkdsa.2002.2.1.27.

Anesthetic Management of the Oral Surgery in a Child with Hemophilia A: A Case Report

• Park CJ
• Lee JH
• Kim HJ
• Yum KW

• KMID: 2345190
• DOI: http://doi.org/10.17245/jkdsa.2002.2.1.27

Abstract

Hemophilia A is the most common congenital bleeding disorder, which is sex-linked disease, caused by a deficiency of clotting factor VIII. We experienced a case of alveolorrhaphy using iliac bone graft under general anesthesia for the correction of bilateral cleft alveolus in 10-year-old boy with hemophilia A. Factor VIII activity in this patient was 0.7%, on the severely deficient level, and aPTT was 100 seconds. Just before operation, he received 1,750 units of factor VIII intravenously for loading dose. After we confirmed his factor VIII activity improved to 95% and aPTT to 38.4 seconds, operation was begun. No more transfusion was needed during the operation. In his postoperative care, he received 50 units/kg a 12 hours for 3 days and 30 units/kg a 12 days for 2 days. His factor VIII activity was maintained at 57-139% during his hospitalization. He was discharged without any anesthetic complication. So we report this successful case of anesthetic management for the oral surgery in a child with hemophilia A

Keyword

Anesthesia; Hemophilia; Oral surgery

MeSH Terms

Anesthesia
Anesthesia, General
Child*
Factor VIII
Hemophilia A*
Hemorrhage
Hospitalization
Humans
Male
Postoperative Care
Surgery, Oral*
Transplants
Factor VIII