J Dent Anesth Pain Med.  2021 Jun;21(3):261-268. 10.17245/jdapm.2021.21.3.261.

An anesthetic management of head and neck cancer reconstructive surgery in a patient having hemophilia A: a case report

Affiliations
  • 1Department of Dental Anesthesiology, School of Dentistry, Seoul National University, Seoul, Republic of Korea
  • 2Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University, Seoul, Republic of Korea

Abstract

Hemophilia A is a hemorrhagic disease caused by coagulation factor VIII deficiency. In head and neck cancer surgery, especially during a reconstructive one, complications can occur. These include hematomas due to bleeding which can then lead to flap ischemia, necrosis, and impaired wound healing. There are fewer cases of reconstructive surgery in patients with hemophilia A. Here in we report, a reconstructive surgery that involved mass resection, partial glossectomy (right), selective neck dissection (right, Levels I, II, III, IV), and reconstruction at the lateral arm free flap (left) in a 25-year-old man with hemophilia A. The surgery was successfully performed without any complications after pretreatment with Factor VIII concentrate, which has not been reported earlier.

Keyword

Factor VIII; Hemophilia A; Reconstructive Surgical Procedures; Squamous Cell Carcinoma of Head and Neck
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