J Korean Dent Soc Anesthesiol.
2009 Dec;9(2):104-107. 10.17245/jkdsa.2009.9.2.104.
Paradoxical Reaction to Midazolam Used in Intravenous Sedation for Dental Treatment: Report of a Case and Review of the Literature
- Affiliations
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- 1Division of Oral and Maxillofacial Surgery, Department of Dentistry, College of Medicine, Hanyang University, Seoul, Korea. fastchang@hanyang.ac.kr
- 2Division of Orthodontics, Department of Dentistry, College of Medicine, Hanyang University, Seoul, Korea.
- KMID: 2345101
- DOI: http://doi.org/10.17245/jkdsa.2009.9.2.104
Abstract
- Midazolam, one of the most common benzodiazepine derivatives, is widely used in intravenous sedation for dental treatment without severe complications. However, paradoxical reactions to midazolam, including patient's unanticipated restlessness, agitation, hostility, and rage, have been frequently reported since the introduction of benzodiazepine. During outpatient intravenous sedation using midazolam for dental treatment, we experienced a paradoxical reaction to midazolam in a 28-year-old female patient. With a thorough review of the literature, the management of this complication and its various etiologies were discussed.
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Cited by 1 articles
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A retrospective study of deep sedation with concomitant administration of sedative agents in children undergoing surgical removal of a mesiodens
Soo Jeong Lee, Kwangwoo Baek
J Dent Anesth Pain Med. 2015;15(4):213-220. doi: 10.17245/jdapm.2015.15.4.213.
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