Korean J Anesthesiol.  2016 Aug;69(4):413-416. 10.4097/kjae.2016.69.4.413.

Suspected anaphylactic reaction associated with sugammadex: a case report

• Yoo JH
• Kim SI
• Ok SY
• Park SY
• Cho A
• Han YM
• Jun MR

• KMID: 2344612
• DOI: http://doi.org/10.4097/kjae.2016.69.4.413

Abstract

We describe a case of a 35-year-old male patient who was scheduled for laparoscopic cholecystectomy and developed a life-threatening anaphylactic reaction 2 min after the administration of sugammadex. He manifested erythematous wheals on the entire body, dyspnea, hypotension, and tachycardia. These symptoms disappeared after the administration of epinephrine. The patient recovered and was discharged at postoperative day 5 without any complications. After 7 weeks, we performed a skin prick test, and there was a weakly positive reaction for sugammadex. This case is suspected anaphylaxis associated with sugammadex, and we need to be aware that the use of sugammadex is associated with a serious risk of anaphylaxis.

Keyword

Anaphylaxis; Sugammadex

MeSH Terms

Adult
Anaphylaxis*
Cholecystectomy, Laparoscopic
Dyspnea
Epinephrine
Humans
Hypotension
Male
Skin
Tachycardia
Epinephrine