J Korean Neurol Assoc.  2000 Jul;18(4):503-507.

A Case of Chronic Inflammatory Demyelinating Polyneuropathy in a 13-year-old Girl with Pes Cavus Deformity

• Kang NJ
• Kim EJ
• Kim DS
• Jung DS
• Park KH

Abstract

Chronic inflammatory demyelinating polyneuropathy (CIDP) is an immune-mediated polyneuropathy with a relaps-ing or progressive course. Although the occurrence of CIDP is very rare in childhood compared to the occurrence in adulthood, it does occur in children. In childhood CIDP, the main clinical features are somewhat different from that of adults, which includes a more precipitous onset of symptoms, a high frequency of gait abnormalities, and significant neurological dysfunction. Also, the response to immune-modulating therapy is more reliable and rapid in children than in adults. The recognition of childhood CIDP is important as it may mimic hereditary neuropathies which usually pre-sent with progressive gait disturbance associated with pes cavus deformity. A careful history, clinical examination, and electrophysiological study is crucial for the accurate diagnosis of this treatable disease. Here, we report a case of CIDP in a 13-year-old Korean girl whose initial clinical presentation strongly suggested hereditary motor-sensory neuropathy.

Keyword

Chronic inflammatory demyelinating polyneuropathy; Hereditary motor-sensory neuropathy; Childhood; Pes cavus; Nerve conduction study

MeSH Terms

Adolescent*
Adult
Child
Congenital Abnormalities*
Diagnosis
Female*
Foot Deformities*
Gait
Humans
Polyneuropathies*
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating