J Korean Neuropsychiatr Assoc.  1998 Sep;37(5):771-782.

Performance of Verbal Memory Tasks in Patients with Schizophrenia

Affiliations
  • 1Department of Psychiatry, Yongdong Severance Hospital, College of Medicine, Yonsei University, Seoul, Korea.

Abstract


OBJECTIVES
Memory deficits in patients with schizophrenia have been well established, but it is still unclear how memory performance changes during verbal learning tasks. This study was designed to assess the pattem of verbal learning and memory performance to test the inefficiency of encoding processes in learning of schizophrenia. METHOD: Subjects consisted of 26 patients with schizophrenia who were unmedicated for atleast seven days and 22 normal controls who were matched for age,sex,and education. Verbal memory and learning were evaluated with computerized tasks composed of three consecutive immediate recall trials, a yes/no recognition test, and a delayed recall trial of a word list.
RESULTS
Thepatients with schizophrenia showed significant learning deficits characterized by impaired immediate recall performance and poor learning of a word list. However, both verbal recognition performance and forgetting were comparable in both groups. Word clustering correlated significantly with recall performance. Clustering of patients decreased significantly over immediate and delay recall tasks and showed poor increase during consecutive recall tasks.
CONCLUSION
Thest findings indicate that verbal learning and mnemonic strategy are impaired but learned information appears to be preserved in patients with schizophrenia. The results are consistent with the notion that a learning deficit is closely related with impaired encoding precesses in schizophrenia.

Keyword

Schizophrenia; Verbal memeory; Learning; Forgetting; Encoding

MeSH Terms

Education
Humans
Learning
Memory Disorders
Memory*
Memory, Short-Term
Schizophrenia*
Verbal Learning
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