J Korean Neuropsychiatr Assoc.  1997 Nov;36(6):1099-1105.

Effects of Cigarette Smoking on Auditory Event-Related Potential P300

• Chun CM
• Kim BK
• Lee CU
• Han SI
• Paik IH

Abstract

OBJECTIVES
The authors studied the effects of cigarette smoking on the cognitive function with topographic mapping of auditory event-related potential P300.
METHODS
The subjects, 24 smokers and 14 nonsmokers, were assessed in the latencies and amplitudes of topographic auditory event-related potential P300 determined by Global Field Power Measurement.
RESULTS
1) There were significant differences of P300 latencies between smokers and controls artier smoking(ANOVAL F=10.45, P=0.0026). 2) There were no significant differences of P300 amplitude but a trend was present between smokers and nonsmokers after smoking(ANOVAL F=3.77, P=0.06). 3) There were no significant differences of difference between amplitude in maximal point and amplitude in minimal point but a trend was present between smokers and nonsmokers artier smoking(ANOVAL F=3.68, P=0.063). 4) There were no significant differences of maximal point in X-axis and in Y-axis, minimal point in X-axis and in Y-axis of P300 between smokers and nonsmokers artier smoking.
CONCLUSIONS
These results support that auditory event-related potential P300 change by cigarrete smoking is indicative of enhanced cognitive function.

Keyword

Smoking; Auditory event-related potential P300; Topographic mapping; Global field power measurement Cognitive function

MeSH Terms

Evoked Potentials*
Smoke
Smoking*
Tobacco Products*
Smoke