J Korean Soc Biol Psychiatry.  2000 Nov;7(2):180-185.

Comparison of Global Field Power Measurement and Conventional Method in Multi-channel Auditory Event Related Potential P300 Determination

Abstract


OBJECTIVE
The present study was designed to compare Global field Power Measurement and conventional method in P300 determination. METHOD: The subjects were composed of patients(N=20) with schizophrenia by DSM-IV and normal controls(N=20). The auditory event related potential P300 was measured by "oddball paradigm". P300 components were determined by Global Field Power Measurement and conventional method at 5 electrodes(Fz, Cz, Pz, T3, T4).
RESULTS
P300 amplitudes of patients were smaller than those of controls across all electrodes and in both methods, but there was no differential power in P300 determination between two methods. Asymmetry of auditory event-related potential P300 was not shown between patients with schizophrenia and normal controls.
CONCLUSION
It is implicated that it depends on clinical situations and research purposes what method of P300 determination will be more appropriate for patients with schizophernia.


MeSH Terms

Diagnostic and Statistical Manual of Mental Disorders
Electrodes
Event-Related Potentials, P300
Evoked Potentials
Humans
Schizophrenia
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