J Korean Oncol Nurs.  2008 Aug;8(2):120-127.

Risk Factors of Breast Cancer

• Chung BY
• Byun HS
• Kim KD
• Kim KH

Abstract

PURPOSE: The purpose of this study was secondary analysis to explore about risk factors with breast cancer on a basis of primary literature. METHODS: This study was searched articles by using CINAHL, MEDLINE, Riss4u, Internet website regarding breast cancer. This study searched for the journal published in Korea and foreign countries from 2000 to 2008, about risk factors of breast cancer. This study was reviewed 42 articles (5 experimental study, 35 survey, 1 qualitative study, 1 report) suitable for the research objectives. RESULTS: Magnitude of risk breast cancer (++) was age, geographic region, family history, mutations in BRCA1, BRCA2 genes and in other penetrance genes, radiation, history of benign breast disease, late age of menopause, early age of menarch, nulliparity and older age at first birth, high mammographic breast density, high insulin-like growth factor 1 level. Magnitude of risk factor (+) was hormone replacement therapy, oral contraceptives use, obesity, tall stature, alcohol consumption, high prolactin level, high saturated fat and well-done meat intake, polymorphisms in low penetrance gene, high socioeconomic status. CONCLUSION: A breast cancer screening protocol according to magnitude of risk factors is needed for disease prevention. The nurses need to educate and counsel women with risk factors of breast cancer.

Keyword

Breast cancer; Risk factors

MeSH Terms

Alcohol Drinking
Birth Order
Breast
Breast Diseases
Breast Neoplasms
Contraceptives, Oral
Female
Genes, BRCA2
Hormone Replacement Therapy
Humans
Internet
Korea
Mass Screening
Meat
Menopause
Obesity
Parity
Penetrance
Prolactin
Risk Factors
Social Class
Contraceptives, Oral
Prolactin