J Korean Ophthalmol Soc.  2012 May;53(5):647-651.

Use of Prophylactic Antibiotics in Glaucoma Surgery: A Single Center's Experience

Affiliations
  • 1Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. sungeye@gmail.com

Abstract

PURPOSE
To evaluate the use of prophylactic antibiotics in glaucoma surgery and the prevalence of postoperative endophthalmitis.
METHODS
Retrospective medical record review was performed on 136 eyes which underwent glaucoma operation by one surgeon from March 2008 to February 2010 and were followed at least till 6 months postoperatively (glaucoma drainage device implantation; 95 eyes, trabeculectomy; 41 eyes).
RESULTS
For intravenous antibiotics injection, 10 eyes used 3rd generation cephalosporin, 54 eyes used 4-fluoroquinolone, 72 eyes used 2nd generation cephalosporin. For oral antibiotics, 125 eyes used 3rd generation cephalosporin, 1 case used 4-fluoroquinolone, and other 10 cases did not use oral antibiotics after the surgery. Total period of systemic antibiotics use showed various distributions with 14 eyes more than 5 days, 115 eyes 4-5 days, and 8 cases less than 4 days. Six eye which used 4-fluoroquinolone and 3 eyes which used cephalosporin showed side effect such as skin lesion and nausea. There has been no single occurrence of endophthalmitis.
CONCLUSIONS
Various kinds of prophylactic antibiotics were used for glaucoma surgery and the period of antibiotics use was different among patients. However, there has been no single occurrence of endophthalmitis till 6 months postoperative follow up.

Keyword

Antibiotics; Endophthalmitis; Glaucoma surgery

MeSH Terms

Anti-Bacterial Agents
Drainage
Endophthalmitis
Eye
Follow-Up Studies
Glaucoma
Humans
Medical Records
Nausea
Prevalence
Retrospective Studies
Skin
Anti-Bacterial Agents

Figure

  • Figure 1 Histogram regarding the period of hospital admission.

  • Figure 2 Histogram regarding the period of systemic antibiotics use.


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