Korean J Obstet Gynecol.  2004 Oct;47(10):1880-1885.

Comparative Study of Single-dose Prophylactic Antibiotics after Cord Clamping Vs. Multi-dose Postoperative Antibiotics in Operative Complications after Elective Cesarean Section

• Baek JK
• Lee WS
• Kim JM
• Lee IH
• Cho YK
• Yang JH

Abstract

OBJECTIVE
To compare single-dose prophylactic antibiotics after cord clamping with multi-dose postoperative antibiotics in operative complications after elective cesarean section.
METHODS
Forty-five women undergoing elective cesarean section had 1g cefazolin administration after umbilical cord clamping. Forty-five women was control group who had antibiotics administration postoperatively 4 times 1 g cefazolin and 5 days more per oral. Postoperative complication including febrile morbidity, wound infection, endometritis, urinary tract infection, pneumonia were recorded, as were the duration of hospital stay and the need for therapeutic antibiotics.
RESULTS
Postoperative complication incuding febrile morbidity, wound infection, endometritis, urinary tract infection, pneumonia had no difference between two groups significantly. Also, their hospital stay had no difference significantly.
CONCLUSION
Single-dose prophylactic antibiotics administration after cord clamping in elective cesarean section is considered to have no difference in comparison with multi-dose post-operative administration. Single-dose prophylactic antibiotics administration after cord clamping will reduce side effect of drugs and resistance. Also it will provide better cost effectiveness.

Keyword

Cesarean section; Prophylactic antibiotics

MeSH Terms

Anti-Bacterial Agents*
Cefazolin
Cesarean Section*
Constriction*
Cost-Benefit Analysis
Endometritis
Female
Humans
Length of Stay
Pneumonia
Postoperative Complications
Pregnancy
Umbilical Cord
Urinary Tract Infections
Wound Infection
Anti-Bacterial Agents
Cefazolin