Prophylactic antibiotics in elective cesarean section

Min, Kyung Soo; Kim, Heung Seo; Lee, Min A; Kim, Yong Il; Seo, Young Seok; Lee, Ki Hwan; Rhee, Yun Ee

Abstract

OBJECTIVE
To evaluate effectiveness of short-course administration of prophylactic antibiotics in elective cesarean section compared with multiple, long-course administration.
METHODS
Forty women undergoing elective cesarean section had prophylactic antibiotics administration preoperatively and 2 times more within 24 hours after operation. Forty women was control group who had antibiotics administration postoperatively 5 or 6 times with multiple regimens and 7 days more per oral. Postpartum complications including febrile morbidity, endometritis, wound infection, urinary tract infection were recorded, as were the duration of hospital stay and need for therapeutic antibiotics.
RESULTS
Postpartum complications including febrile morbidity, endometritis, wound infection and urinary tract infection had no difference between two groups significantly. Also, their hospital stay had no difference significantly.
CONCLUSION
Prophylactic and short-course antibiotics administration in elective cesarean section is considered to have no difference in comparison with multiple, long-course post-operative administration. Short- course prophylactic antibiotics administration will reduce side effect of drugs and resistance. Also it will provide better cost effectiveness.