J Korean Ophthalmol Soc.  2012 Feb;53(2):208-214.

Long-Term Endothelial Cell Changes after Angle-Supported Anterior Chamber Lens Implantation in Phakic Eyes

• Yang J
• Lee JK

Abstract

PURPOSE
To evaluate long-term endothelial cell changes in phakic eyes that underwent implantation of an angle-supported anterior chamber lens to correct myopia.
METHODS
A retrospective analysis was performed in 110 eyes of 55 patients who underwent implantation of angle-supported anterior chamber lenses with a follow-up period longer than 5 years. Comparisons were made between preoperative and postoperative endothelial cell density, coefficient of variation, and percentage of hexagonal cells.
RESULTS
Mean preoperative corneal endothelial cell density was 2951 +/- 336 cells/mm2 and the percentage of cell loss was 3.8% at year 1, 12.6% at year 3, 13.4% at year 5, 22.5% at year 7, and 22.2% at year 9. Explantation was required in 13 eyes (11.8%) due to the decrease of endothelial cell count to 936 +/- 458 cells/mm2 over 9 years of follow-up.
CONCLUSIONS
Continuous endothelial cell loss was observed after implantation of angle-supported anterior chamber lens in the long-term follow-up. A constant decline in the endothelial cell density necessitates periodic ophthalmologic evaluation including specular microscopy.

Keyword

Angle-supported anterior chamber lens; Endothelial cell loss

MeSH Terms

Anterior Chamber
Endothelial Cells
Eye
Follow-Up Studies
Humans
Microscopy
Retrospective Studies

Figure

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  Figure 1 Phakic intraocular lens (PIOL) explantation. Kaplan-Meier survival table. After 112 months of follow-up, 88.18% of cases will retain the PIOL in place.

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