J Korean Ophthalmol Soc.
2004 Sep;45(9):1573-1577.
Primary Localized Amyloidosis of the Lacrimal Gland
- Affiliations
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- 1Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University, School of Medicine, Seoul, Korea. ydkim@smc.samsung.co.kr
Abstract
- PURPOSE
Primary localized amyloidosis of the lacrimal gland is rarely encountered in the lacrimal gland. The authors report a patient with orbital amyloidosis isolated to the lacrimal gland. METHODS: A 52-year-old woman presented with the superotemporal orbital mass for one year. The patient underwent surgical biopsy. RESULTS: A representative tissue section, stained with hematoxylin and eosin, showed pink amorphous hyaline deposits diffusely infiltrating tissue. The hyaline deposits stained positively with Congo red and demonstrated birefringence under polarized light. Immunohistochemical stains against immunoglobulin light chain were positive against kappa and lambda chain. No systemic involvement was noted from systemic work-up. Primary localized amyloidosis of the lacrimal gland was diagnosed. CONCLUSIONS: As far as we know this is the first case of primary localized amyloidosis of the lacrimal gland in Korea. Amyloidosis should be considered in differential diagnosis of a mass in the lacrimal gland.
