J Korean Ophthalmol Soc.
2004 Sep;45(9):1567-1572.
Primary Localized Amyloidosis of the Lacrimal Gland
- Affiliations
-
- 1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.
- 2Department of Ophthalmology, Seoul National University Boramae Hospital, Seoul, Korea. hokyung@brm.co.kr
- 3Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Korea.
Abstract
- PURPOSE
Amyloidosis involving the lacrimal gland is a very rare condition. We report our experience with a case of primary localized amyloidosis of the lacrimal gland. METHODS: A 36-year-old woman presented with a palpable mass on the right temporal upper eyelid of 1-month duration. The non-tender, firm, and movable mass was palpable on the area of the right lacrimal gland. There were no abnormalities on slit-lamp biomicroscopic and fundus examinations, nor was proptosis or limitation of extraocular movement seen. Excisional biopsy through Krnlein operation and histopathologic examination were followed by orbital computerized tomography (CT). RESULTS: CT scan revealed a homogeneous soft tissue mass containing focal calcification in the right lacrimal gland. Hematoxylin and eosin stained sections showed pink amorphous hyaline deposits and Congo red-stained sections demonstrated dichroism and birefringence under polarized light microscopy, consistent with the diagnosis of amyloidosis. In an additional study, no systemic involvement was noted. CONCLUSIONS: In any case presenting temporal upper eyelid swelling and homogeneous mass containing focal calcification involving the lacrimal gland on CT scan, amyloidosis should be differentiated and it is necessary to confirm the diagnosis through biopsy and systemic work-up.
