J Korean Ophthalmol Soc.  2019 Nov;60(11):1117-1120. 10.3341/jkos.2019.60.11.1117.

Primary Amyloidosis Localized to the Conjunctiva

• Noh HJ
• Park BC
• Koh JW

• KMID: 2463364
• DOI: http://doi.org/10.3341/jkos.2019.60.11.1117

Abstract

PURPOSE
To report a case of primary amyloidosis localized to the conjunctiva.
CASE SUMMARY
A 19-year-old male with a conjunctival mass and foreign body sensations in the right eye transferred from another hospital. A 0.5 × 2.5 cm reddish mass was present in the medial canthus of the right conjunctiva with no other clinically specific signs. Surgical excisional biopsy was performed. Histological examination showed amyloid deposition. There was no other orbital involvement apart from the conjunctiva. Abnormalities were not found in the systemic examination.
CONCLUSIONS
We report a case of primary amyloidosis localized to the conjunctiva.

Keyword

Amyloidosis; Biopsy; Conjunctival neoplasm

MeSH Terms

Amyloidosis*
Biopsy
Conjunctiva*
Conjunctival Neoplasms
Foreign Bodies
Humans
Lacrimal Apparatus
Male
Orbit
Plaque, Amyloid
Sensation
Young Adult

Figure

• 

  Figure 1 Slit-lamp photograph on the first visit. A reddish diffuse protruding mass in the medial canthal conjunctiva in the right eye (arrow) (A). Surgical excisional biopsy was performed, and the specimen size was 0.5 × 2.5 × 0.2 cm (B).

• 

  Figure 2 Histological features of the conjunctival mass. A hematoxylin and eosin (H&E)-stained section showed amorphous, homogenous, eosinophilic material composed of amyloid (arrows). (A) H&E staining (×200). (B) H&E staining (×400).

• 

  Figure 3 Histological features of the conjunctival mass. A Congo-red-stained section shows orange colored stained amyloid deposits (arrows). (A) Congo red staining (×100). (B) Congo red staining (×400).

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  Figure 4 Slit-lamp photograph at the 6 months after operation. The mass was completely removed, with no recurrence.

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