J Korean Epilepsy Soc.  2002 Dec;6(2):150-153.

Gelastic Seizures in a Patient with Tuberous Sclerosis

Affiliations
  • 1Department of Neurology, Kosin University College of Medicine, Busan, Korea. nekim@ns.kosinmed.or.kr

Abstract

BACKGROUND: Gelastic seizures are characterized by ictal inappropriate sudden laughter as the predominant seizure manifestation. they are very rare and may occur in patients with hypothalamic hamartomas, pituitary tumors, astrocytomas of the mamillary bodies, CNS infection, trauma, and dysraphic condition. CASE: A 21-year-old woman with tuberous sclerosis was admitted due to frequent sudden inappropriate laughter as a seizure manifestation. EEG showed paroxysmal brief generalized 4-5 Hz spike and wave complexes. Brain MRI revealed multiple tubers in the bilateral cerebral cortical areas, right caudate nucleus, and left anterior cingulate gyrus. We tried vigabatrin, but gelastic seizures were not controlled. COMMENT: We report a case of gelastic seizures associated with tuberous sclerosis, which has not previously been reported in Korea.

Keyword

Gelastic seizures; Tuberous sclerosis

MeSH Terms

Astrocytoma
Brain
Caudate Nucleus
Electroencephalography
Female
Gyrus Cinguli
Hamartoma
Humans
Korea
Laughter
Magnetic Resonance Imaging
Mamillary Bodies
Pituitary Neoplasms
Seizures*
Tuberous Sclerosis*
Vigabatrin
Young Adult
Vigabatrin
Full Text Links
  • JKES
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2023 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr