J Korean Soc Emerg Med.  2006 Oct;17(5):505-508.

A Case of Churg-Strauss Syndrome

• Han SK
• Kim IS
• Jeong WJ
• Yi HY
• Lee WS
• Ryu S
• Yoo IS

Abstract

Churg-Strauss syndrome is a rare syndrome that affects small to medium sized arteries and veins. The American College of Rheumatology has proposed six criteria for the diagnosis of Churg-Strauss syndrome. These criteria are asthma, eosinophilia 10% in peripheral blood, paranasal sinusitis, pulmonary infiltrates, histological proof of vasculitis with extravascular eosinophils, mononeuritis multiplex or polyneuropathy. If at least 4 of these 6 criteria are positive, a patient shall be said to have Churg-Strauss syndrome. We report a case of a 70-year-old woman who had presented with polyneuropathy, hemorrhagic bullae and petechiae on both the legs and the arms. Previously, she had been diagnosed with asthma. Laboratory studies revealed peripheral blood eosinophilia. Water's view showed mucoperiosteal thickening and hazziness in both of the maxillary sinus. A skin biopsy revealed perivascular leukocytoclastic infiltration with marked eosinophilic infiltration. The patient was treated with prednisolone and a skin graft. Within a few days of prednisolone treatment, the clinical presentation improved with the exception of peripheral polyneuropathy.

Keyword

Churg-Strauss syndrome; Asthma; Eosinophila

MeSH Terms

Aged
Arm
Arteries
Asthma
Biopsy
Churg-Strauss Syndrome*
Diagnosis
Eosinophilia
Eosinophils
Female
Humans
Leg
Maxillary Sinus
Mononeuropathies
Polyneuropathies
Prednisolone
Purpura
Rheumatology
Sinusitis
Skin
Transplants
Vasculitis
Veins
Prednisolone