J Korean Soc Endocrinol.  1997 Jun;12(2):315-320.

A Case of Central Diabetes Insipidus Developed during Puerperium

• Yoo SJ
• Lee KW
• Son HY
• Kang SK
• Chung MH
• Choi BS
• Cha BY

Abstract

Diabetic insipidus may first present before, during or immediately after pregnancy. Pregnancy serves as a physiologic provocation test that unmasks latent diabetes insipidus. It may explain the very rare first occurrence of diabetes insipidus in the pureperium. Central diabetes insipidus occurring after delivery associated with a catastrophic delivery and postpartum hypopituitarism is more frequent entity. We recently experienced central diabetes insipidus patient, aggrevated polyuria and polydipsia after total hysterectomy due to cervical carcinoma, who had interesting past history of severe polyuria and polydipsia developed during puerperium of 1st pregnancy, 14 years ago. She have had quiet normal pregnancy and there was no definite postpartum complication of pregnancy at that time. There were no change of polyuria and polydipsia during and after second pregnancy and 2 another pregnancy terminated artificially compare to puerperium of 1st delivery. She has intact anterior pituitary gland functinally and anatomically, but the posterior pituitary hyperintense signal with pre-enhance Tl-weighted imaging was absent on MRI.

MeSH Terms

Diabetes Insipidus
Diabetes Insipidus, Neurogenic*
Humans
Hypopituitarism
Hysterectomy
Magnetic Resonance Imaging
Pituitary Gland, Anterior
Polydipsia
Polyuria
Postpartum Period*
Pregnancy