Kosin Med J.  2011 Jun;26(1):98-102.

Central Diabetes Insipidus Occurring during Therapy for Tsutsugamushi Disease

Affiliations
  • 1Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea. aiteite1@naver.com

Abstract

Tsutsugamushi disease (Scrub typhus) is an acute febrile illness caused by infection with Orientia tsutsugamushi and characterized by focal or disseminated vasculitis, which may involve the lungs, heart, liver and central nervous system. Tsutsugamushi meningitis are reported worldwide, but central diabetes insipidus associated with CNS involvement have not been reported. A 53-year-old female diagnosed with tsutsugamushi disease showed polyuria during therapy with doxycycline. After injection of vasopressin, urine output was decreased and urine osmolarity was increased. So, we diagnosed as central diabetic insipidus. We report a case of central diabetes insipidus occurring during therapy for tsutsugamushi disease.

Keyword

Diabetes insipidus; Orienta tsutsugamushi

MeSH Terms

Central Nervous System
Diabetes Insipidus
Diabetes Insipidus, Neurogenic
Doxycycline
Female
Heart
Humans
Liver
Lung
Meningitis
Middle Aged
Orientia tsutsugamushi
Osmolar Concentration
Polyuria
Scrub Typhus
Vasculitis
Vasopressins
Doxycycline
Vasopressins
Full Text Links
  • KMJ
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr