J Korean Child Neurol Soc.
2014 Jun;22(2):52-57.
Electroencephalographic Features of Rasmussen's Encephalitis by Stage
- Affiliations
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- 1Department of Pediatrics, Seoul National University Bundang Hospital, Gyeonggi-do, Korea. hunminkim@hanmail.net
- 2Department of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.
- 3Pediatric Clinical Neuroscience Center, Seoul National University Children's Hospital, Seoul, Korea.
- 4Department of Pediatrics, SMG-SNU Boramae Hospital, Seoul, Korea.
Abstract
- PURPOSE
The purpose of this study was to describe the characteristic electroencephalographic features in Rasmussen's encephalitis by stage.
METHODS
Patients diagnosed with Rasmussen's encephalitis at Seoul National University Children's Hospital were retrospectively assessed. We analyzed the background activities and epileptiform discharges from electroencephalography (EEG) findings to identify the characteristic EEG features by stage.
RESULTS
Seven patients were included in the study. The mean age of first seizure onset was 6.7 years, and the mean duration of the prodromal phase was 21.4 months. During disease course, background activities, such as slow waves, were more prominent and diffuse, and contralateral slow waves were observed. In most patients, focal epileptiform discharges were observed during all stages without change.
CONCLUSION
As Rasmussen's encephalitis progresses, background abnormalities in the affected hemisphere increased, and contralateral slow waves occurred. However, characteristic EEG findings that were distinguishable at each stage were not observed.
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