Korean J Intern Med.
2016 Jul;31(4):730-738. 10.3904/kjim.2014.328.
Liver cirrhosis leads to poorer survival in patients with end-stage renal disease
- Affiliations
-
- 1Department of Internal Medicine, Gachon University Gil Medical Center, Graduate School of Medicine, Gachon University, Incheon, Korea. jhchang@gilhospital.com
- KMID: 2327749
- DOI: http://doi.org/10.3904/kjim.2014.328
Abstract
- BACKGROUND/AIMS
Liver cirrhosis (LC) is an important problem in patients withend-stage renal disease (ESRD). Few studies have investigated the inf luence ofLC on mortality in patients with ESRD. This study investigated the associationbetween LC and mortality among patients with ESRD and compare mortality betweentwo dialysis modalities.
METHODS
Adult patients (≥ 18 years of age) starting dialysis for ESRD were enrolledin the present study from 2000 to 2011. We analyzed 1,069 patients withESRD; of these, 742 patients were undergoing hemodialysis (HD) and 327 patientswere undergoing peritoneal dialysis (PD).
RESULTS
The prevalence of LC was 44 of 1,069 patients (4.1%). The cumulative 1-,3-, and 5-year survival rates of noncirrhotic patients were 93%, 83%, and 73%, respectively,whereas the equivalent survival rates of cirrhotic patients were 90%,68%, and 48%, respectively (p = 0.011). After adjustment, LC was an independentrisk factor for death in patients with ESRD. No difference in mortality associatedwith LC was found between the HD and PD subgroups.
CONCLUSIONS
Of the patients with ESRD, cirrhotic patients had poorer survivalthan noncirrhotic patients. Among patients with ESRD and LC, survival of patientsundergoing PD may be comparable with that of patients undergoing HD.
