J Menopausal Med.  2014 Dec;20(3):85-89. 10.6118/jmm.2014.20.3.85.

Effective Anti-aging Strategies in an Era of Super-aging

Affiliations
  • 1Department of Health and Functional Food, College of Medical Science, Korea. jslee11@jj.ac.kr
  • 2Food Industry Research Institute, Korea.
  • 3The Health and Science Research Institute, Jeonju University, Jeonju, Korea.

Abstract

The societies of the world in the 21st century have faced challenges arising from an aging population as the fertility rate has dropped dramatically and medical advances have extended the average human life span. The elderly aged 65 years or older make up at least 20% of the population in Korea, making the country a super-aging society as defined by the United Nations. The number of elderly women is higher than that of elderly men and women live longer than men. Based on the analysis of recent trends in previous studies, this study aimed to suggest practical strategies to utilize isoflavones, substances chemically similar to the female hormone estrogen, and to search for effective anti-aging strategies using this substance for women to be prepared to reach the elderly stage in good health.

Keyword

Anti-aging; Estrogen; Female; Hormone replacement therapy; Isoflavone; Quality of life

MeSH Terms

Aged
Aging
Birth Rate
Estrogens
Female
Hormone Replacement Therapy
Humans
Isoflavones
Korea
Male
Quality of Life
United Nations
Estrogens
Isoflavones

Reference

1. OECD. Pensions at a glance 2013: OECD and G20 indicators. Seoul: OECD/Korea Policy Centre;2014.
2. Shin SJ. Problems and countermeasures of low birth rate and aging society. J Korean Hosp Assoc. 2005; 34:4–6.
3. Cho DH, Ma SR. Old age security pension policies and reverse mortgages. Paju: Jipmoon;2007.
4. Suh HJ. Korea's aging society and it's problems. Minjok Yeonku. 2011; 48:25–40.
5. Jang HJ. Industrial restructuring and women's labor market: focusing on the financial industry. J Korean Womens Stud. 2000; 16:35–74.
6. Lee HJ, Sung MO, Shin YA. A study on the psychological well-being and depression of urban elderly women. J Welf Aged. 2003; 22:127–150.
7. Kwon JD. A study on the casual factors of elderly abuse. J Korea Gerontol Soc. 2004; 24:1–19.
8. Lee H. Current conditions and prospects of women's movements in community: a case study of Chinju area. J Korean Womens Stud. 1999; 15:103–152.
9. Cho BS, Kim H, Ku SY. Role of estrogen in sex dimorphism of longevity. J Reprod Med Popul. 2011; 24:42–51.
10. Hyun J, Jung Y. Potential roles of hedgehog and estrogen in regulating the progression of fatty liver disease. J Life Sci. 2011; 21:1795–1803.
11. Min G. Inhibitory effects of high concentrations of estrogen, progesterone and tamoxifen on proliferation of HeLa in culture. J Life Sci. 2011; 21:1746–1751.
12. Ferry B, Roozendaal B, McGaugh JL. Basolateral amygdala noradrenergic influences on memory storage are mediated by an interaction between beta- and alpha1-adrenoceptors. J Neurosci. 1999; 19:5119–5123.
13. Yeo E. Menopause, aging and obesity. J Korean Soc Study Obes. 2002; 11:289–298.
14. Kim MJ. The effects of aerobic exercise on the healthrelated physical fitness factors, bone mineral density, and estrogen foe menopausal women with long-term HRT and menopausal women without HRT. J Korea Sport Res. 2007; 18:587–598.
15. Han JK. The impact of long term combined exercise on aging related hormone in elderly women. Exerc Sci. 2008; 17:23–30.
16. Kim EJ, Kim JS, Yoon JH. The impact of Gichejo for mental and physical training on middle-aged women's body composition and aging-related hormone. Exerc Sci. 2013; 22:239–247.
17. Kim JD. Effect of Takwondo training and resistance training difference on aging related hormones and obese index of elderly women. J Sport Leis Stud. 2013; 51:687–697.
18. Ham YG, Park BK. Effects of dance sports training on estrogen and growth hormone in middle-aged women. Korean J Exerc Nutr. 2010; 14:69–73.
19. Gwak JH, Kim JY, Kim HJ, Shin DH, Lee JH. The effect of isoflavone and gamma-linolenic acid supplementation on serum lipids and menopausal symptoms in postmenopausal women. Korean J Nutr. 2010; 43:123–131.
20. Martinez J, Lewi JE. An unusual case of gynecomastia associated with soy product consumption. Endocr Pract. 2008; 14:415–418.
21. Siepmann T, Roofeh J, Kiefer FW, Edelson DG. Hypogonadism and erectile dysfunction associated with soy product consumption. Nutrition. 2011; 27:859–862.
22. Hamilton-Reeves JM, Vazquez G, Duval SJ, Phipps WR, Kurzer MS, Messina MJ. Clinical studies show no effects of soy protein or isoflavones on reproductive hormones in men: results of a meta-analysis. Fertil Steril. 2010; 94:997–1007.
23. Mitchell JH, Cawood E, Kinniburgh D, Provan A, Collins AR, Irvine DS. Effect of a phytoestrogen food supplement on reproductive health in normal males. Clin Sci (Lond). 2001; 100:613–618.
24. Nechuta SJ, Caan BJ, Chen WY, Lu W, Chen Z, Kwan ML, et al. Soy food intake after diagnosis of breast cancer and survival: an in-depth analysis of combined evidence from cohort studies of US and Chinese women. Am J Clin Nutr. 2012; 96:123–132.
25. Khan SA, Chatterton RT, Michel N, Bryk M, Lee O, Ivancic D, et al. Soy isoflavone supplementation for breast cancer risk reduction: a randomized phase II trial. Cancer Prev Res (Phila). 2012; 5:309–319.
26. Kim SY, Kim SY, Chung CE, Yoon S, Park JH. Effects of isoflavone supplementation on lipid profiles and antioxidant systems in rats fed with cholesterol diet. J Life Sci. 2000; 20:1683–1690.
27. Ferry B, Roozendaal B, McGaugh JL. Role of norepinephrine in mediating stress hormone regulation of longterm memory storage: a critical involvement of the amygdala. Biol Psychiatry. 1999; 46:1140–1152.
Full Text Links
  • JMM
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr