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Chimeric Antigen Receptor T Cell Therapy: A Novel Modality for Immune Modulation

Yoon S, Eom GH

Cancer remains a leading cause of death, despite multimodal treatment approaches. Even in patients with a healthy immune response, cancer cells can escape the immune system during tumorigenesis. Cancer cells...
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Immunohistochemical Study of Fas/Fas-ligand and Cadherin Expression in Basal Cell Carcinoma in Sun-Exposed and Sun-Protected Areas

Kim JH, Suh HS, Choi YS

  • KMID: 2465949
  • Korean J Dermatol.
  • 2019 Sep;57(8):425-432.
BACKGROUND: UV radiation is the most important risk factor in the development of basal cell carcinoma (BCC). However, the association between tumorigenesis and the progression of BCC and UV exposure...
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Comparative Study of Health Care System in Three Central Asian Countries: Kazakhstan, Kyrgyzstan, Uzbekistan

Dronina Y, Nam EW

BACKGROUND: The objectives of the study are to find out the effect of the implementing reform in three Central Asian countries, identify its impact on health status and health care...
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Cellular immunotherapy in multiple myeloma

Vo MC, Lakshmi TJ, Jung SH, Cho D, Park HS, Chu TH, Lee HJ, Kim HJ, Kim SK, Lee JJ

In multiple myeloma (MM), the impaired function of several types of immune cells favors the tumor’s escape from immune surveillance and, therefore, its growth and survival. Tremendous improvements have been...
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Death and Survival of Patients with Hansen's Disease in Colonial Korea

Kim JH

The purpose of this research is to describe how Hansen's disease patients experienced the modern system of control of Hansen's disease introduced by Japan, and the inimical attitude of society...
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Influence of Short- and Long-term High-dose Caffeine Administration on Behavior in an Animal Model of Adolescence

Park JM, Kim Y, Kim H, Kim YJ

PURPOSE: Caffeine is the most widely consumed psychostimulant of the methylxanthine class. Among adolescents, high-dose of caffeine consumption has increased rapidly over the last few decades due to the introduction...
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The Interpretation of the Opera ‘Die Zauberflöte, K.620 ’ Focused on Psychosexual Development

Kang JW, Kim T, Ha JH

Freud wrote that art is the product of the conscience of an artist. He interpreted artistic works in psychoanalytic ways, such as “Leonardo da Vinci and a Memory of His...
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Eye irritation tests of polyhexamethylene guanidine phosphate (PHMG) and chloromethylisothiazolinone/methylisothiazolinone (CMIT/MIT) using a tissue model of reconstructed human cornea-like epithelium

Park J, Lee H, Park K

Disinfectants including polyhexamethylene guanidine phosphate (PHMG) and mixtures of chloromethylisothiazolinone/methylisothiazolinone (CMIT/MIT) have been widely used in Korea to prevent microbial growth in the humidifier water, which triggered an outbreak of...
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Implication of hepatocyte dedifferentiation in pathogenesis and treatment of hepatocellular carcinoma

Kim HS, Park EJ, Lee CW

Liver cancer is the fifth most common malignancy worldwide and the third most common cause of cancer-related death. Five hundred million individuals are infected by hepatitis B or C virus....
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Victim-oriented digital disaster emergency medical system

Ahn ME, Lee TH, Kim DW

The fatality rate of a disaster is associated with the impact of the disaster and the case fatality rate. The severity of the disaster can be reduced by an efficient...
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Experiencing Coercive Control in Female Victims of Dating Violence

Kwon J, Park S

BACKGROUND: Dating violence refers to violence occurring between people in an intimate relationship. Forms of dating violence are often categorized into physical, psychological, and sexual violence, and most existing literature...
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Triploidy that escaped diagnosis using chromosomal microarray testing in early pregnancy loss: Two cases and a literature review

Park JE, Park JK, Kang MY, Jo HC, Cho IA, Baek JC

About 15% to 20% of all clinically recognized pregnancies result in spontaneous abortion or miscarriage, and chromosomal anomalies can be identified in up to 50% of first trimester miscarriages. Chromosomal...
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PD-1: A Negative Regulator of Phagocytosis by Tumour-Associated Macrophages in Colon Cancer

Islam Tultul MS, Koh YS

Programmed cell death protein 1 (PD-1) is an immuno-inhibitory cell surface receptor protein of the myeloid, and lymphoid cell. PD-L1 is the ligand of PD-1, which is abundant in different...
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Hemorrhagic Fever with Renal Syndrome

Noh JY, Jung J, Song JW

In Korea, hemorrhagic fever with renal syndrome (HFRS) was first reported in a United Nations (UN) soldier stationed in the central front, also known as the “Iron Triangle”. In 1976,...
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Functional analysis of prv-miR-LLT11a encoded by pseudorabies virus

Liu H, Yang L, Shi Z, Lv R, Yang X, Wang C, Chen L, Chang H

Viral-encoded microRNAs (miRNAs) have vital roles in the regulation of virus replications and host immune responses. The results of previous studies have indicated that miRNA clusters are involved in the...
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microRNAs in Mycobacterial Infection: Modulation of Host Immune Response and Apoptotic Pathways

Agarwal RG, Sharma P, Nyati KK

Our current knowledge of mycobacterial infections in humans has progressively increased over the past few decades. The infection of Mycobacterium tuberculosis causes tuberculosis (TB) disease, which has reasoned for excessive...
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Immune-related Adverse Events: Overview and Management Strategies for the Use of Immune Checkpoint Inhibitors

Jeung HC, Oh SE, Kim JH

Recent studies on T cell immunology have been instrumental in developing therapies to overcome cancer immune escape, and immune checkpoint inhibitors have emerged as one of the most promising therapeutic...
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Iodine Deficiency in Neonates: Where Do We Stand After a Quarter Century of Initiating Iodization Programs?

Jafri L, Majid H, Ahmed S, Siddiqui I, Ghani F, Khan AH

An observational study was conducted at the Section of Clinical Chemistry, Department of Pathology and Laboratory Medicine, to assess the iodine status using the World Health Organization (WHO), United Nations...
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International Health Cooperation and Challenges for Official Development Assistance

Nam EW

As the United Nations announced Sustainable Development Goals (SDGs) in 2015, the world changed its development goals from focusing on efficiency to equity. As a result, in the health sector,...
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Ideology of Social Health Insurance and Health Policy

Lee KS

Health care has two different facets. One is commodity and another is a right of human being. Health care as a commodity is utilized by demand approach in market. Demand...
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