J Korean Soc Transplant.
2003 Dec;17(2):197-202.
Venous Complications after Pediatric Liver Transplantation
- Affiliations
-
- 1Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. kmkim@amc.seoul.kr
- 2Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
- 3Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
- 4Department of Pediatrics, Asan Hospital, University of Ulsan College of Medicine, Gang Neung, Korea.
Abstract
- PURPOSE
We performed this study to assess the incidence of venous complications, including portal vein and hepatic vein stenosis, in both split cadaveric and living donor liver transplants and to assess the diagnostic and therapeutic modalities of these lesions.
METHODS
Seventy-six liver transplantations were performed in 75 children with split (5) or living donor (71) graft between December 1994 and March 2002. Patients' data were analyzed retrospectively with special emphasis on venous complications.
RESULTS
Venous complications occurred in 14 patients (18.6%) including hepatic vein stenosis in 8, portal vein stenosis in 4, portal vein thrombosis in 1, and combined portal vein thrombosis and hepatic artery stenosis in 1 patient. Venous complications were accompanied by abnormality of liver fuction, ascites, progressed splenomegaly, and gastrointestinal bleeding. To diagnose the venous complications, Doppler ultrasonography was performd at first, and those were confirmed by angiography or CT. Hepatic vein stenosis was managed by percutaneous transhepatic angioplasty (6), angioplasty followed by reposition of graft (1), and supportive care only 1 patient. Portal vein complications were managed by angioplasty (4), angioplasty followed by mesocaval shunt (1), and combined revascularization and angioplasty (1). The overall survival rate was 86% (12 of 14 patients).
CONCLUSION
Close surveillance of the complication of vascular anastomoses and multidisciplinary approach to treat of venous complication after pediatric liver transplantation have made it possible to reduce the graft loss and mortality. Aggressive and successful radiologic intervention should be considered to eliminate the need for surgical revision, portacaval shunting or retransplantation.
MeSH Terms
-
Angiography
Angioplasty
Ascites
Cadaver
Child
Constriction, Pathologic
Hemorrhage
Hepatic Artery
Hepatic Veins
Humans
Incidence
Liver Transplantation*
Liver*
Living Donors
Mortality
Portacaval Shunt, Surgical
Portal Vein
Reoperation
Retrospective Studies
Splenomegaly
Survival Rate
Transplants
Ultrasonography, Doppler
Venous Thrombosis
