J Korean Acad Rehabil Med.  2003 Aug;27(4):622-625.

Gabapentin-induced Neutropenia: A case report

• Lee PK
• Jung JY
• Park SM
• Kim EJ

Abstract

Gabapentin, a novel anti-convulsant, is recently used to manage symptomatic treatment of neuropathic pain. Gabapentin is known to have few side effect profiles such as drowsiness, dizziness, somnolence, and nausea. We experienced a case of neutropenia associated with gabapentin. A 74-year-old man was hospitalized because of left side weakness caused by acute thalamocortical infarction. He complained of tingling sen- sation, aching pain, and dysesthesia on his left side. We prescribed gabapentin to manage his symptoms. Fever developed at 22 days of gabapentin therapy and peripheral blood examination revealed neutropenia. At 2 days after stopping gabapentin, neutrophil counts started to revert.

Keyword

Gabapentin; Neutropenia; Neuropathic pain

MeSH Terms

Aged
Dizziness
Fever
Humans
Infarction
Nausea
Neuralgia
Neutropenia*
Neutrophils
Paresthesia
Sleep Stages