Tuberc Respir Dis.  2009 Jan;66(1):27-32.

Clinical Characteristics and Prognosis of Lung Cancer Patients Admitted to the Medical Intensive Care Unit at a University Hospital

• Moon KM
• Han MS
• Lee SK
• Jeon HS
• Lee YD
• Cho Y
• Na DJ

Abstract

BACKGROUND
The management of patients with lung cancer has improved recently, and many of them will require admission to the medical intensive care unit (MICU). The aim of this study was to examine the clinical characteristics and to identify risk factors for mortality in patients with lung cancer admitted to the MICU.
METHODS
We conducted retrospective analysis on 88 patients with lung cancer admitted to the MICU between April 2004 and March 2008.
RESULTS
Of the 88 patients (mean age, 66 years), 71 patients (80.7%) had non-small cell lung cancer and 17 patients (19.3%) had small cell lung cancer. Distant metastasis were present in 79 patients (89.8%). The main reasons for MICU admission were acute respiratory failure (77.3%), sepsis (11.4%), and central nervous system dysfunction (4.5%). Mechanical ventilation was used in 54 patients (61.4%). Acute Physiology and Chronic Health Evaluation (APACHE) II score, length of MICU stay, need for mechanical ventilation, source of MICU admission were correlated with MICU mortality. The type of lung cancer and metastasis were not predictive factors of death in MICU.
CONCLUSION
Most common reason for ICU admission was acute respiratory failure. Mortality rate of lung cancer patients admitted to the MICU was 65.9%. APACHE II score, length of ICU stay, need for mechanical ventilation, source of MICU admission were predicted factors of death in the MICU.

Keyword

Lung cancer; Intensive care unit; APACHE II score; Mechanical ventilation

MeSH Terms

APACHE
Carcinoma, Non-Small-Cell Lung
Central Nervous System
Humans
Critical Care
Intensive Care Units
Lung
Lung Neoplasms
Neoplasm Metastasis
Prognosis
Respiration, Artificial
Respiratory Insufficiency
Retrospective Studies
Risk Factors
Sepsis
Small Cell Lung Carcinoma

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