Tuberc Respir Dis.  2006 Oct;61(4):398-402.

Lung Cancer Presented as Painful Swelling of Lower Legs

• An JY
• Lee JE
• Park HW
• Lee JH
• Yang SA
• Park YK
• Lee SR

Abstract

Trousseau's syndrome comsists of migratory thrombophlebitis and thromboembolic disorders of the venous and arterial systems in a malignancy or occult cancer. The overall incidence has been reported to vary from 1 to 11%. Pancreatic, lung, prostate, and stomach cancer is associated with the greatest risk of thromboembolic events. We encountered a 49-year-old man who presented with painful swelling of his lower legs. The chest radiograph showed increased opacity of the Left middle lung fields and Doppler sonography showed a thrombus in the left superficial femoral vein. Chest Computed Tomography showed a 5cm sized left hilar mass invading the pericardium with lymphadenopathy. The bronchoscope biopsy demonstrated an adenocarcinoma of the lung. Platinum based chemotherapy and anticoagulant therapy with warfarin was carried out. The patient was later discharged with an improvement in the painful swelling of his lower legs.

Keyword

lung cancer; Trousseau's syndrome

MeSH Terms

Adenocarcinoma
Biopsy
Bronchoscopes
Drug Therapy
Femoral Vein
Humans
Incidence
Leg*
Lung Neoplasms*
Lung*
Lymphatic Diseases
Middle Aged
Pericardium
Platinum
Prostate
Radiography, Thoracic
Stomach Neoplasms
Thorax
Thrombophlebitis
Thrombosis
Warfarin
Platinum
Warfarin

Figure

• 

  Figure 1 Chest radiograph shows increased opacity of Left middle lung fields.

• 

  Figure 2 Chest Computed tomography(CT) shows 5 cm sized Left hilar mass invading pericardium with lymphadenopathy.

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  Figure 3 Abdomen Computed tomography(CT) shows diffuse thrombosis from infrarenal level of Inferior vena cava (A) to both superfical femoral (B)

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