Tuberc Respir Dis.  2003 Oct;55(4):395-401.

A Case of Pulmonary Tuberculosis with Delayed Diagnosis Due to the Temporary Clinical Improvement After Use of Levofloxacin and Amikacin Under the Impression of Community Acquired Pneumonia

Affiliations
  • 1Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, and Lung Institute, Seoul National University College of Medicine, Korea. yimjj@snu.ac.kr

Abstract

Fluoroquinolone is one of the first-line antibiotics recommended for treating community-acquired pneumonia. However, using fluroquinolones for presumptive community-acquired pneumonia can delay the diagnosis and the treatment of pulmonary tuberculosis because of its strong activity against mycobacteria. Here, we report a case of a 54-year-old female taking immunosuppressants after a renal transplant whose diagnosis of pulmonary tuberculosis was delayed as a result of the use of levofloxacin and amikacin under the original impression of community-acquired pneumonia. This case suggests that clinicians should consider the possibility of pulmonary tuberculosis in the case of a partial response of the pneumonia to flouroquinolones and/or aminoglycosides.

Keyword

Levofloxacin; Amikacin; Pulmonary tuberculosis; Pneumonia; Delayed diagnosis

MeSH Terms

Amikacin*
Aminoglycosides
Anti-Bacterial Agents
Delayed Diagnosis*
Diagnosis
Female
Humans
Immunosuppressive Agents
Levofloxacin*
Middle Aged
Pneumonia*
Tuberculosis, Pulmonary*
Amikacin
Aminoglycosides
Anti-Bacterial Agents
Immunosuppressive Agents
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