Soonchunhyang Med Sci.  2015 Dec;21(2):192-196. 10.0000/sms.2015.21.2.192.

Bone Marrow Recurrence with Microscopic Pulmonary Tumor Embolism after Excision of Extramammary Paget's Disease in Scrotum Three Years Ago

• Cho S
• Kim JW
• Youk J
• Hwang SM
• Park HJ
• Lee CT

• KMID: 2317788
• DOI: http://doi.org/10.0000/sms.2015.21.2.192

Abstract

Here we report a case of a 72-year-old male patient recurred in bone marrow alone with pulmonary tumor embolism after an excision of extramammary Paget's disease of scrotum 3 years ago. The patient received paclitaxel/carboplatin chemotherapy with respiratory support in intensive care unit. Four days after chemotherapy, the oxygen demand decreased and the patient was transferred to general ward. The platelet count recovered after 2 weeks. Finally, he died of hepatic failure from Paget's disease hepatic involvement confirmed by liver biopsy at 10 months after recurrence. This is a rare case of recurred extramammary Paget's disease in bone marrow alone with pulmonary tumor embolism, which was properly diagnosed with high suspicion and was successfully treated with immediate chemotherapy.

Keyword

Extramammary Paget's disease; Pulmonary hypertension; Pulmonary embolism; Neoplastic cells, circulating; Scrotum

MeSH Terms

Aged
Biopsy
Bone Marrow*
Drug Therapy
Humans
Hypertension, Pulmonary
Intensive Care Units
Liver
Liver Failure
Male
Neoplastic Cells, Circulating*
Oxygen
Paget Disease, Extramammary*
Patients' Rooms
Platelet Count
Pulmonary Embolism
Recurrence*
Scrotum*
Oxygen