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Liver Graft Failure and Bile Cast Nephropathy

Mrzljak A, Jurekovic , Novak R, Maksimovic B, Mikulic D, Galesic Ljubanovic D

The consequences of graft failure after liver transplantation (LT) range far beyond the liver. The kidneys are often affected, where persistent and progressive cholestasis can result in acute kidney injury...
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What are the most important predictive factors for clinically relevant posthepatectomy liver failure after right hepatectomy for hepatocellular carcinoma?

Navarro JG, Yang SJ, Kang I, Choi GH, Han DH, Kim KS, Choi JS

PURPOSE: The risk of posthepatectomy liver failure (PHLF) after right hepatectomy remains substantial. Additional parameters such as computed tomography volumetry, liver stiffness measurement by FibroScan, indocyanine green retention rate at...
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Comparison study for surgical outcomes of right versus left side hemihepatectomy to treat hilar cholangiocellular carcinoma

Hong SS, Han DH, Choi GH, Choi JS

PURPOSE: Major liver resection and radical lymph node dissection has been accepted as a definite treatment of choice for hilar cholangiocarcinoma (HC). However, the perioperative and survival outcomes of right...
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Autoimmune Hepatic Failure Following Acute Hepatitis A is Accompanied by Inflammatory Conversion of Regulatory T Cells

Leem G, Kim BK, Shin EC, Park JY

To evaluate the pathophysiology of autoimmune hepatitis (AIH) following acute hepatitis A (AHA) in immunologic aspects, we performed multi-color flow cytometry with peripheral blood mononuclear cells of a patient who...
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New Predictive Model of Short-term Survival in Acute Liver Failure by Acute Hepatitis A

Heo NY

No abstract available.
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Radioembolization for the Treatment of Primary and Metastatic Liver Cancers

Lee EJ, Chung HW, Jo JH, So Y

Radioembolization using ⁹⁰Y microspheres (glass or resin) has been introduced as an effective intraarterial therapy for unresectable primary and metastatic liver cancers. Although the basic therapeutic effect of chemoembolization results...
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Successful Treatment of Neonatal Herpes Simplex Infection Presenting as Fulminant Hepatitis with Acyclovir and Peritoneal Dialysis

Choi S, Lee JH, Park MS

Disseminated neonatal herpes simplex virus (HSV) infection is a severe disease with a high mortality rate. Here, we report the patient presented with fulminant hepatic failure secondary to HSV infection...
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Novel ATP8B1 Gene Mutations in a Child with Progressive Familial Intrahepatic Cholestasis Type 1

Rhee ES, Kim YB, Lee S, Oh SH, Lee BH, Kim KM, Yoo HW

Progressive familial intrahepatic cholestasis (PFIC) is a group of severe genetic disorders, inherited in an autosomal recessive manner, causing cholestasis of hepatocellular origin, later progressing to biliary cirrhosis and liver...
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The Use of Foxa2-Overexpressing Adipose Tissue-Derived Stem Cells in a Scaffold System Attenuates Acute Liver Injury

Chae YJ, Jun DW, Lee JS, Saeed WK, Kang HT, Jang K, Lee JH

BACKGROUND/AIMS: For the clinical application of stem cell therapy, functional enhancement is needed to increase the survival rate and the engraftment rate. The purpose of this study was to investigate...
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Implication of hepatocyte dedifferentiation in pathogenesis and treatment of hepatocellular carcinoma

Kim HS, Park EJ, Lee CW

Liver cancer is the fifth most common malignancy worldwide and the third most common cause of cancer-related death. Five hundred million individuals are infected by hepatitis B or C virus....
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Rapid progression of sarcomatoid carcinoma of the common bile duct

Kim MJ, Lee JS, Kim YM, An S, Yoon YC

Since sarcomatoid carcinoma in the common bile duct (CBD) is rarely reported, the clinical course and prognosis after surgery are unclear. We report a case of a patient who died...
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Evaluation of bioenergetic and mitochondrial function in liver transplantation

Martins RM, Teodoro JS, Furtado E, Rolo AP, Palmeira C, Tralhão J

BACKGROUND/AIMS: We measured changes in mitochondrial function and bioenergetics that occur during ischemia/reperfusion in fresh liver samples of patients undergoing liver transplantation. These variations correlated with markers of liver function...
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Hepatobiliary Manifestation of Inflammatory Bowel Disease

Seo KI, Kang SB

The hepatobiliary system is one of the most common sites of extraintestinal manifestation in patients with inflammatory bowel disease (IBD). The progression of IBD can lead to a primary hepatobiliary...
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A Rare Case of Lethal Prenatal-Onset Infantile Cortical Hyperostosis

Kim ST, Kim H, Kim HH, Lee NH, Han Y, Sung SI, Chang YS, Park WS

Infantile cortical hyperostosis, or Caffey's disease, usually presents with typical radiological features of soft tissue swelling and cortical thickening of the underlying bone. The disease can be fatal when it...
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Hepatic failure caused by acute fatty liver of pregnancy treated by orthotopic liver transplantation: A case report

Bang YS, Ko D, Lee S, Lee S, Park C

Acute fatty liver of pregnancy (AFLP) is unusual but can potentially progress to overwhelming liver failure, resulting in maternal and fetal death. AFLP is characterized by the accumulation of microvesicular...
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A Case of Spontaneous Rupture of Hepatocellular Carcinoma Supplied by the Right Renal Capsular Artery Treated by Transcatheter Arterial Embolization

Jang JY, Jeon UB, Kim JH, Kim TU, Ryu H, Cho M, Hong YM, Kim M

We present a case of spontaneous rupture of hepatocellular carcinoma with poor liver function managed by transcatheter arterial embolization (TAE). The patient's bilirubin level was 2.1 mg/dL, albumin level was...
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Hepatic Failure Due to Hepatitis E Virus Infection in a Patient with Necrotic Hepatocellular Carcinoma

Kim JH, Doh YS, Jang JW, Kang MS, Kim NM, Kim SH, Baek IH, Jung SH

In patients with hepatocellular carcinoma (HCC) or liver cirrhosis (LC) accompanied by hepatitis E virus (HEV) infection, hepatic failure often leads to debility. Here, we report about a 63-year-old man...
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Conditioned Medium from Tonsil-Derived Mesenchymal Stem Cells Relieves CClâ‚„-Induced Liver Fibrosis in Mice

Kim YH, Cho KA, Park M, Kim HS, Park JW, Woo SY, Ryu KH

BACKGROUND: The liver is an organ with remarkable regenerative capacity; however, once chronic fibrosis occurs, liver failure follows, with high mortality and morbidity rates. Continuous exposure to proinflammatory stimuli exaggerates...
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Favorable effect of corticosteroids in treating acute-on-chronic liver failure underlying chronic hepatitis B

Kim H, Kwon JH, Kim YH, Nam SW, Lee JY, Jang JW

Acute-on-chronic liver failure (ACLF) occurs in the presence of a chronic liver disease or cirrhosis, and often results from exacerbation of chronic hepatitis B (CHB). The efficacy of corticosteroid treatment...
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Severe acute alcoholic hepatitis and liver transplant: A never-ending mournful story

Obed A, Bashir A, Stern S, Jarrad A

Severe acute alcoholic liver disease (SAAH) unresponsive to medical therapy shows one-year-mortality rates of up to 90%. Most transplant centers request six months of alcohol abstinence prior to transplantation, the...
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