Soonchunhyang Med Sci.  2011 Dec;17(2):151-154.

A Case of Successful Treatment for Stiff Man Syndrome

Affiliations
  • 1Department of Rehabilitation Medicine, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea. seok50503@daum.net

Abstract

Stiff man syndrome is a rare neurological condition characterized by progressive muscle stiffness and rigidity, painful spasm of axial and limb muscles with impairment of walking. Because its etiology is still unclear, diagnosis is based on typical clinical manifestations. Benzodiazepines are known as effective drug for the treatment of symptoms. We report a case of 39-year-old female patient who has suffered from rigidity of trunk, back pain, gait disturbance and depressive mood for 18 months. She was diagnosed as stiff man syndrome and successfully treated with medications such as diazepam, clonidine, baclofen.

Keyword

Stiff man syndrome; Rigidity; Anti glutamate decarboxylase antibody

MeSH Terms

Adult
Back Pain
Baclofen
Benzodiazepines
Clonidine
Diazepam
Extremities
Female
Gait
Humans
Muscles
Spasm
Stiff-Person Syndrome
Walking
Baclofen
Benzodiazepines
Clonidine
Diazepam
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