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Clinical Characteristics and Risk Factors for Mortality in Critical Coronavirus Disease 2019 Patients 50 Years of Age or Younger During the Delta Wave: Comparison With Patients > 50 Years in Korea

Shi HJ, Nham E, Kim B, Joo EJ, Cheong HS, Hong SH, Hyun M, Kim Ha, Jang S, Rhee JY, Kim J, Kim S, Cho HK, Wi YM, Cheon S, Kim YS, Lim S, Seok H, Jung SI, Eom JS, Peck KR

Background: Numerous patients around the globe are dying from coronavirus disease 2019 (COVID-19). While age is a known risk factor, risk analysis in the young generation is lacking. The present...
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Risk Factors for Coronavirus Disease 2019 (COVID-19)-Associated Pulmonary Aspergillosis in Critically Ill Patients: A Nationwide, Multicenter, Retrospective Cohort Study

Kim SH, Hong JY, Bae S, Lee H, Wi YM, Ko JH, Kim B, Joo EJ, Seok H, Shi HJ, Yoo JR, Hyun M, Kim Ha, Jang S, Mun SJ, Kim J, Kim MC, Jung DS, Kim SH, Peck KR

Background: Coronavirus disease 2019 (COVID-19) is often accompanied by secondary infections, such as invasive aspergillosis. In this study, risk factors for developing COVID-19-associated pulmonary aspergillosis (CAPA) and their clinical outcomes...
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Hypertrophic Cardiomyopathy in Infants from the Perspective of Cardiomyocyte Maturation

Seok H, Oh JH

Hypertrophic cardiomyopathy (HCM) is characterized by ventricular wall hypertrophy with diastolic dysfunction. Pediatric HCM is distinguished from the adult in many aspects. Most children with HCM do not present clinically...
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When We Consider Neurolymphomatosis in Patient with Lumbosacral Plexopathy with an Extreme Leg Pain?

Ahn JY, Seok H, Kim SH, Kim HJ, Cho YH, Oh BM, Lee SY

We report a case of neurolymphomatosis of lumbosacral plexus. A 63-year-old man, who had no past history except for diabetes mellitus, complained of severe pain and weakness on left lower...
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Application of CRISPR-Cas9 gene editing for congenital heart disease

Seok H, Deng R, Cowan DB, Wang DZ

Clustered regularly interspaced short palindromic repeats and CRISPR-associated protein 9 (CRISPR-Cas9) is an ancient prokaryotic defense system that precisely cuts foreign genomic DNA under the control of a small number...
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Speech-aid prosthesis in velopharyngeal incompetency patient with cleft palate: can speech aids be applicable for adult patient?

Kang DC, Park JH, Seok H, Baek JA, Kim DW, Ko SO

Background: Velopharyngeal incompetence (VPI) therapy for cleft palate (speech therapy alone, speech therapy using speech aids, or combined therapy such as speech therapy using a pharyngeal flap), is more effective...
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Ultrasonographic Analysis of Optimal Needle Placement for Extensor Indicis

Kim JY, Seok H, Kim SH, Choi YH, Ahn JY, Lee SY

Objective To determine the most optimal needle insertion point of extensor indicis (EI) using ultrasound. Methods A total 80 forearms of 40 healthy volunteers were recruited. We identified midpoint (MP) of...
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Trend of Olfactory and Gustatory Dysfunction in COVID-19 Patients in a Quarantine Facility

Seo MY, Seok H, Hwang SJ, Choi HK, Jeon JH, Sohn JW, Park DW, Lee SH, Choi WS

Background: Olfactory and gustatory dysfunction has been reported as characteristic symptoms of coronavirus disease 2019 (COVID-19). This study evaluated olfactory and gustatory dysfunction in mild COVID-19 patients using validated assessment...
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Korean Registry for Improving Sepsis Survival (KISS): Protocol for a Multicenter Cohort of Adult Patients with Sepsis or Septic Shock

Kim JH, Ku NS, Kim YJ, Kim HB, Seok H, Lee DG, Lee JS, Jeong SJ, Choi JH, Sohn JW, Kim MJ, Park DW

Sepsis is one of the significant causes of morbidity and mortality. The burden caused by sepsis has continued to increase in recent years in the Korea, highlighting the urgent need...
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Antimicrobial Therapy and Antimicrobial Stewardship in Sepsis

Seok H, Jeon JH, Park DW

Since sepsis was first defined, sepsis management has remained challenging. To improve mortality rates for sepsis and septic shock, an accurate diagnosis and prompt administration of appropriate antibiotics are essential....
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A New Member of Myocardial Ischemia-Reperfusion (MI/R) Associated miRNAs, miR-484: Its Potential Cardiac Protection Role

Seok H

No abstract available.
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Optimal antimicrobial therapy and antimicrobial stewardship in sepsis and septic shock

Seok H, Park DW

The management of sepsis and septic shock remains challenging. The aim is to apply the optimal antimicrobial therapy and antimicrobial stewardship to patients in state of sepsis or septic shock....
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Letter: Efficacy and Safety of Voglibose Plus Metformin in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial (Diabetes Metab J 2019;43;276-86)

Seok H, Sohn TS

No abstract available.
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A Paragonimiasis Mimicking Gastric Submucosal Tumor

Seok H, Sohn TS, Peck KR

No abstract available.
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Botulinum toxin A injection into the anterior belly of the digastric muscle increased the posterior width of the maxillary arch in developing rats

Ahn J, Kim SG, Kim MK, Jang I, Seok H

BACKGROUND: The purpose of this study was to evaluate the effects of botulinum toxin A (BTX) injection into the anterior belly of the digastric muscle on a growing rat. METHODS: Ten...
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Failure of Ciprofloxacin Therapy in the Treatment of Community-Acquired Acute Pyelonephritis caused by In-Vitro Susceptible Escherichia coli Strain Producing CTX-Type Extended-Spectrum β-Lactamase

Seok H, Cha MK, Kang CI, Cho SY, Kim SH, Ha YE, Chung DR, Peck KR, Song JH

While carbapenems are the drug of choice to treat extended-spectrum-β-lactamase (ESBL)-producing strains, some alternative carbapenem-sparing regimens are suggested for antibiotic stewardship. We experienced a case of ciprofloxacin treatment failure for...
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Comparison Between Neuromuscular Electrical Stimulation to Abdominal and Back Muscles on Postural Balance in Post-stroke Hemiplegic Patients

Park M, Seok H, Kim SH, Noh K, Lee SY

OBJECTIVE: To compare the effects of neuromuscular electrical stimulation (NMES) to abdominal muscles and back muscles on postural balance in post-stroke hemiplegic patients. METHODS: Thirty post-stroke hemiplegic patients were prospectively enrolled...
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Immediate Effects of Mental Singing While Walking on Gait Disturbance in Hemiplegic Stroke Patients: A Feasibility Study

Lee SY, Seok H, Kim SH, Park M, Kim J

OBJECTIVE: To investigate the immediate therapeutic effects of mental singing while walking intervention on gait disturbances in hemiplegic stroke patients. METHODS: Eligible, post-stroke, hemiplegic patients were prospectively enrolled in this study....
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Primary sinonasal mucosal melanoma simulated as cystic lesions: a case report

Shin SH, Seok H, Kim SG, Hong SD

Sinonasal mucosal melanoma (SNMM) in the maxillary sinus is a rare disease condition. Compared to oral mucosal melanoma, SNMM has a bulky, exophytic, and polypoid appearance, is weakly pigmented, and...
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Calcium pyrophosphate dihydrate deposition disease in the temporomandibular joint: diagnosis and treatment

Kwon KJ, Seok H, Lee JH, Kim MK, Kim SG, Park HK, Choi HM

BACKGROUND: Calcium pyrophosphate dihydrate deposition disease (CPDD) is a rare disease in the temporomandibular joint (TMJ) space. It forms a calcified crystal mass and induces a limitation of joint movement. CASE...
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