- Abuse Liability of Baclofen
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Praharaj S
- KMID: 2405244
- Clin Psychopharmacol Neurosci.
- 2018 Feb;16(1):126-127.
- doi: 10.9758/cpn.2018.16.1.126
No abstract available. -
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- A Case of Baclofen-induced Encephalopathy
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Kim JH, Kang JK, Kwak KW, Lee SA
- KMID: 2342808
- J Korean Neurol Assoc.
- 2000 May;18(3):337-340.
We report a case of acute transient encephalopathy with mental alteration, myoclonic jerks, and periodic triphasic wave electroencephalographic patterns caused by a therapeutic dose of baclofen. The clinical and electroencephalo-graphic... -
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- Successful Treatment of Persistent Hiccups with Baclofen and Gabapentin: A case report
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Kim WO, Yoon KB, Kil HK, Yoon DM, Cho KS, Cho MJ
- KMID: 2237576
- Korean J Anesthesiol.
- 2004 Jul;47(1):142-145.
- doi: 10.4097/kjae.2004.47.1.142
Persistent hiccups are described as a recurring troublesome series of involuntary inspirations accompanied by glottic closure, lasting longer than a month. Recently, baclofen, the most effective treatment for intractable... -
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- A Case Report of Acute Transient Encephalopathy Induced by Low Dose Baclofen
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Ryu HC, Lim JS, Cho KY, Choi SM
- KMID: 2134436
- Chonnam Med J.
- 2004 Sep;40(3):158-160.
Baclofen has been reported to elicit various neurologic complications, such as encephalopathy, respiratory depression, muscular hypotonia and generalized hyporeflexia, especially with excessive doses. However, acute encephalopathy caused by low-dose baclofen... -
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- Experimental Verification of Drug Interaction between Warfarin and Baclofen
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Ko HY, Park JH, Shin YB
- KMID: 2323341
- J Korean Acad Rehabil Med.
- 1999 Dec;23(6):1151-1154.
OBJECTIVE: A warfarin-baclofen interaction has been postulated, but has not been documented in the literature. The purpose of this study is to investigate the drug interaction between warfarin and baclofen... -
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- Baclofen Abuse due to Its Hypomanic Effect in Patients with Alcohol Dependence and Comorbid Major Depressive Disorder
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Ghosh S, Bhuyan D
- KMID: 2378490
- Clin Psychopharmacol Neurosci.
- 2017 May;15(2):187-189.
- doi: 10.9758/cpn.2017.15.2.187
Baclofen is a gamma-aminobutyric acid type B receptor agonist used as an anti-craving agent for treatment of alcohol dependence. It has gained popularity in the recent times because it is... -
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- A Case of Baclofen-Induced Encephalopathy in a Patient with ESRD on Continuous Ambulatory Peritoneal Dialysis
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Kim EH, Kim B, Lee SJ, Kim MH, Kang SW, Chio KH, Yoo TH
- KMID: 1834874
- Korean J Nephrol.
- 2011 Mar;30(2):211-214.
Baclofen (beta-4-chlorophenyl-gamma-aminobutyric acid), a gamma-aminobutyric acid (GABA) derivative, is commonly used for relief of spinal-origin spasm or pain. Baclofen is eliminated predominantly by the kidneys, putting patients with impaired renal... -
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- Effects of Intrathecal Baclofen on Spasticity
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Chung YK, Lim CS, Chung HS, Lee HG, Lee KC, Chu JW
- KMID: 1953088
- J Korean Neurosurg Soc.
- 1989 Jan;18(1):59-65.
9 patients with spasticity of cerebral or spinal cord origin have been maintained for upto 2 months with intermittent bolus spinal intrathecal infusion of baclofen. Prior to treatment, all of... -
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- Probable Interaction between Warfarin and Baclofen: A report of two cases
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Ko HY, Park JH, Kim H
- KMID: 2323132
- J Korean Acad Rehabil Med.
- 1998 Jun;22(3):761-764.
OBJECTIVE: To present two cases of probable warfarin and baclofen interactions which occurred during the concomitant drug administrations. CASE SUMMARY: In the first case, a 55-year-old man with C6 ASIA C... -
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- A Case of Intractable Hiccup Controlled by Combination Drug Therapy with Levosulpiride, Omeprazole and Baclofen
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Kim KR, Kim MR, Ha CK, Choi SH
- KMID: 2195083
- J Korean Neurol Assoc.
- 2003 Jun;21(3):318-319.
No abstract available. -
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- Effects of Orally Administered Baclofen in the Animal Model for Neuropathic Pain
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Lee JS, Yoon SH, Oh SC, Lee WH, Kim HJ, Choi SJ
- KMID: 2090883
- Korean J Anesthesiol.
- 1995 Jan;28(1):23-34.
- doi: 10.4097/kjae.1995.28.1.23
The aim of this study was to compare with the effects of baclofen using an animal model of neuropathic pain. The sciatic nerve of rats was ligated unilaterally about dorsal... -
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- Adverse Side Effect of Baclofen: Case Report
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Kim DY, Choi SM, Kim YS, Oh SH, Lee J
- KMID: 1960281
- J Korean Acad Rehabil Med.
- 1997 Feb;21(1):229-233.
Baclofen(B-4-chlorphyl-r-amino butyric acid), a centrally acting gamma amino butyric acid (GABA) agonist is a commonly used pharmaceutics for spasticity of spinal cord lesion. It's effect includes activation of GABA recep... -
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- Treatment of Intractable Hiccups With an Oral Agent Monotherapy of Baclofen: A Case Report
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Lee JH, Kim TY, Lee HW, Choi YS, Moon SY, Cheong YK
- KMID: 2392745
- Korean J Pain.
- 2010 Mar;23(1):42-45.
Hiccups are an involuntarily powerful spasm of the diaphragm, followed by a sudden inspiration with a closure of the glottis. Hiccups that are caused by gastric distention, spicy foods and... -
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- Effect of Baclofen on the Cholinergic Nerve Stimulation in Isolated Rat Detrusor
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Lee KY, Lee KM, Choi EM, Choi HC, Ha JH, Kim WJ
- KMID: 2320375
- Yeungnam Univ J Med.
- 1995 Dec;12(2):246-259.
- doi: 10.12701/yujm.1995.12.2.246
This study aimed to investigate the mechanism of action of baclofen on the detrusor muscle isolated from rat. Rats (Sprague-Dawley) were sacrificed by decapitation and exsanguination. Horizontal muscle strips of... -
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- Arbaclofen Placarbil Decreases Reflux With Good Tolerability in Patients With Gastroesophageal Reflux Disease (Am J Gastroenterol 2010;105:1266-1275)
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Kim GH
- KMID: 2204245
- J Neurogastroenterol Motil.
- 2010 Oct;16(4):444-445.
No abstract available. -
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- Acquired Periodic Alternating Nystagmus
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No YJ, Lee SA
- KMID: 2137953
- J Korean Neurol Assoc.
- 2004 Oct;22(5):548-551.
Periodic alternating nystagmus is a rare form of horizontal jerk nystagmus characterized by a periodical reversal in the direction of nystagmus. It implies a cerebellar disorder or lesions involving the... -
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- Epidural Baclofen in the Rabbit: Antinociceptive Effect and Neurotoxicity
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Lim YJ, Kim YC, Lee SC, Choe GY, Ahn WS
- KMID: 2091581
- Korean J Anesthesiol.
- 2000 Dec;39(6):882-888.
- doi: 10.4097/kjae.2000.39.6.882
BACKGROUND: Intrathecal baclofen has an analgesic effect. However, the analgesic effect and neurotoxicity of epidural baclofen has not been reported. METHODS: Twenty rabbits, weighing 2.5-3.0 kg, were randomly assigned to... -
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- Brain Functional Magnetic Resonance Imaging Cue-reactivity Can Predict Baclofen Response in Alcohol Use Disorders
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Holla B, Karthik S, Biswal J, Viswanath , Jayarajan , Bharath RD, Venkatasubramanian G, Benegal V
- KMID: 2419983
- Clin Psychopharmacol Neurosci.
- 2018 Aug;16(3):290-301.
- doi: 10.9758/cpn.2018.16.3.290
OBJECTIVE: Baclofen is a promising treatment for alcohol use disorders (AUD), although its clinical response in humans is mixed. The present study aimed at investigating the impact of baclofen treatment... -
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- The effect of intrathecal baclofen single injection on neuropathic pain
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Lee CA, Kim HS, Kim HY, Lee GG
- KMID: 2358339
- Anesth Pain Med.
- 2016 Oct;11(4):399-403.
- doi: 10.17085/apm.2016.11.4.399
BACKGROUND: Baclofen is a gamma-aminobutyric acid B-receptor agonist, which is usually used for patients with spasticity or patients with nerve injury inducing both spasticity and neuropathic pain. Both oral administration... -
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- Intrathecal Baclofen for Spasticity: Changes in Clinical Feature and Gait
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Sung DH, Chang DY
- KMID: 2058302
- J Korean Acad Rehabil Med.
- 1998 Dec;22(6):1239-1248.
OBJECTIVE: To know the effect of intrathecal baclofen on increased muscle tone, spasm and ambulation. METHODS: Six patients with a severe chronic spasticity were evaluated with 10~75 microgram of intrathecal baclofen... -
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