Soonchunhyang Med Sci.  2011 Jun;17(1):11-15.

The Analysis of Risk Factors of Gall Stone Associated with Metabolic Syndrome

Affiliations
  • 1Department of Family Medicine, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea. drsjy@schmc.ac.kr

Abstract


OBJECTIVE
Recently, the prevalence of gall stone related with metabolic syndrome is increasing in Korea. The aim of this study was to reveal a relationship between components of metabolic syndrome and the development of gall bladder stones.
METHODS
Among the subjects who visited a health promotion center of Soonchunhyang University Hospital from March 2009 to March 2010, a total of 5,201 adults were examined. Among them, the final 5,052 (male 3,403, female 1,649) adults were included. Sex, age, body mass index, waist circumference, blood pressure, fasting blood glucose, total cholesterol, triglyceride, high density lipoprotein-cholesterol levels, and the presence of gall stones were measured. Metabolic syndrome was defined by criteria of 2004 American Heart Association/Updated National Cholesterol Education Program Adult Treatment Panel III. Analyses were adjusted by age and sex.
RESULTS
This study showed that the prevalence of gall stone was 1.6% and metabolic syndrome was 19.3%. The results didn't show an association between gall stone risk and components of metabolic syndrome. But gall stone risk was increased according to aging, high total cholesterol in the abnormal body mass index group. In normal body mass index group, waist circumference was related with the development of gall stone. Total cholesterol level was related with the development of gall stone in overweight group.
CONCLUSION
This study showed total cholesterol levels and waist circumference related with prevalence of gall stone in specific body mass index group.

Keyword

Metabolic syndrome; Gallstones; Total cholesterol; Waist circumference; Body mass index

MeSH Terms

Adult
Aging
Blood Glucose
Blood Pressure
Body Mass Index
Cholesterol
Fasting
Female
Gallstones
Health Promotion
Heart
Humans
Korea
Overweight
Prevalence
Risk Factors
Urinary Bladder
Waist Circumference
Blood Glucose
Cholesterol
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