Sleep Med Psychophysiol.  2001 Dec;8(2):144-147.

Acute Respiratory Distress due to Rapid Transquilization in a Bipolar Patient with Sleep Apnea

• Ham BJ
• Seo YJ
• Kim L

Abstract

Clinical restraint or "rapid transquilization" is another option in treating patients who are a danger to themselves or others and struggle violently once physically restrained. The most commonly used drugs are benzodiazepines and antipsychotics. The use of benzodiazepines, either alone or in combination with high potency neuroleptics, has increased in recent years. Benzodiazepines are extremely safe but may cause respiratory depression and hypotension. Respiratory depression is more likely with intravenous administration, therefore these medications should be given slowly and titrated to the desired effect. Special care should be taken when sedating patients who are under the influence of alcohol or narcotics and are sleep apneic patients. This report deals with a case of respiratory distress in a patient with sleep apnea syndrome after the rapid tranqulization. All patients receiving chemical restraint must be carefully monitored. For critically ill patients who require sedation or chemical restraint, the constant attendance of a physician may be warranted.

Keyword

Sleep apnea; Rapid tranquilization

MeSH Terms

Administration, Intravenous
Antipsychotic Agents
Benzodiazepines
Critical Illness
Humans
Hypotension
Narcotics
Respiratory Insufficiency
Sleep Apnea Syndromes*
Antipsychotic Agents
Benzodiazepines
Narcotics