Korean J Urol.  2013 Apr;54(4):229-233.

The Establishment of K-CaP (the Multicenter Korean Prostate Cancer Database)

• Lee DH
• Lee SH
• Rha KH
• Choi IY
• Lee JY
• Kim SW
• Lee S
• Hong SK
• Byun SS
• Jeong IG
• Hong JH
• Kim CS
• Jeon HG
• Lee HM
• Chung BH

Abstract

PURPOSE
The purpose of this article was to announce the establishment of the multicenter Korean Prostate Cancer Database (K-CaP) and to provide urologists with details about K-CaP's methodology.
MATERIALS AND METHODS
The initial participating K-CaP institutions include five medical centers in Korea. First, we registered prostate cancer patients who underwent radical prostatectomy as the basic background data. K-CaP is poised to combine these initial observational longitudinal studies with those of other eligible institutions as the database grows. All current prostate cancer patients in Korea are able to be registered into the Web-based database system and thereby have a role in several observational studies. The structure of the database for K-CaP was developed by matching it with the respective data from different studies. The operability of the K-CaP database system was verified by using the existing databases from three participating institutions.
RESULTS
The analysis of clinicopathologic characteristics of patients with the use of the Web-based database was successfully conducted. We confirmed the accurate operation of the Web-based database system without any difficulties.
CONCLUSIONS
We are announcing the establishment of K-CaP the first database of comprehensive observational longitudinal studies about prostate cancer in Korea. The database will be successfully maintained by sufficiently and continuously updating all patient data covering several treatments. Complete statistical results for registered prostate cancer patients are forthcoming for the basic background data to establish the database. Even though much trial and error are expected during the development process, we expect that K-CaP will eventually become one of the most powerful longitudinal observation databases.

Keyword

Database; K-CaP; Korea; Prostate neoplasms

MeSH Terms

Humans
Korea
Longitudinal Studies
Prostate
Prostatectomy
Prostatic Neoplasms

Reference

1. Statistics Korea [Internet]. 2012 Mar 10. Daejeon: Statistics Korea;Available from: http://kostat.go.kr/portal/english/index.action.

2. Jung KW, Park S, Kong HJ, Won YJ, Lee JY, Seo HG, et al. Cancer statistics in Korea: incidence, mortality, survival, and prevalence in 2009. Cancer Res Treat. 2012. 44:11–24.

3. Park SK, Sakoda LC, Kang D, Chokkalingam AP, Lee E, Shin HR, et al. Rising prostate cancer rates in South Korea. Prostate. 2006. 66:1285–1291.

4. Lubeck DP, Litwin MS, Henning JM, Stier DM, Mazonson P, Fisk R, et al. The CaPSURE database: a methodology for clinical practice and research in prostate cancer. CaPSURE Research Panel. Cancer of the Prostate Strategic Urologic Research Endeavor. Urology. 1996. 48:773–777.

5. Cooperberg MR, Broering JM, Litwin MS, Lubeck DP, Mehta SS, Henning JM, et al. The contemporary management of prostate cancer in the United States: lessons from the cancer of the prostate strategic urologic research endeavor (CapSURE), a national disease registry. J Urol. 2004. 171:1393–1401.

6. Akaza H, Usami M, Hinotsu S, Ogawa O, Kagawa S, Kitamura T, et al. Characteristics of patients with prostate cancer who have initially been treated by hormone therapy in Japan: J-CaP surveillance. Jpn J Clin Oncol. 2004. 34:329–336.

7. Lee DH, Lee SH, Lee DH, Chung MS, Chung BH. Are men who undergo radical prostatectomy with lower urinary tract symptoms at an increased risk for aggressive prostate cancer? Korean J Urol. 2011. 52:819–823.

8. Park S, Kim SC, Kim W, Song C, Ahn H. Impact of adjuvant androgen-deprivation therapy on disease progression in patients with node-positive prostate cancer. Korean J Urol. 2011. 52:741–745.

9. Kim YJ, Kim SO, Ryu KH, Hwang IS, Hwang EC, Oh KJ, et al. Prostate cancer can be detected even in patients with decreased PSA less than 2.5 ng/ml after treatment of chronic prostatitis. Korean J Urol. 2011. 52:457–460.

10. Lee SH, Park KK, Chung MS, Chung BH. Clinical features of familial or hereditary prostate cancer in korean men: a pilot study. Korean J Urol. 2011. 52:9–12.

11. Seo HS, Lee NK. Predictors of PSA screening among men over 40 years of age who had ever heard about PSA. Korean J Urol. 2010. 51:391–397.

12. Kwon JK, Chang IH, Kim TH, Myung SC. Changes in prostate cancer pattern according to prostate-specific antigen screening test. Korean J Urol. 2009. 50:439–444.